Risedronate sodium monohydrateProduct ingredient for Risedronic acid
- Name
- Risedronate sodium monohydrate
- Drug Entry
- Risedronic acid
Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's diseaseLabel1,2. It functions by preventing resorption of boneLabel1.
- Accession Number
- DBSALT001516
- Structure
Structure for Risedronate sodium monohydrate (DBSALT001516)
- Synonyms
- Risedronate monosodium monohydrate / Risedronate sodium hydrate
- UNII
- F67L43UT5C
- CAS Number
- 353228-19-0
- Weight
- Average: 323.109
Monoisotopic: 322.99358463 - Chemical Formula
- C7H12NNaO8P2
- InChI Key
- KLQNARDFMJRXSF-UHFFFAOYSA-M
- InChI
- InChI=1S/C7H11NO7P2.Na.H2O/c9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6;;/h1-3,5,9H,4H2,(H2,10,11,12)(H2,13,14,15);;1H2/q;+1;/p-1
- IUPAC Name
- sodium hydrate hydrogen [1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonate
- SMILES
- O.[Na+].OC(CC1=CN=CC=C1)(P(O)(O)=O)P(O)([O-])=O
- External Links
- ChemSpider
- 13447496
- Predicted Properties
Property Value Source Water Solubility 16.5 mg/mL ALOGPS logP -0.59 ALOGPS logP -3.3 Chemaxon logS -1.3 ALOGPS pKa (Strongest Acidic) 0.68 Chemaxon pKa (Strongest Basic) 4.91 Chemaxon Physiological Charge -3 Chemaxon Hydrogen Acceptor Count 8 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 151.01 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 56 m3·mol-1 Chemaxon Polarizability 21.53 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon