Tiletamine hydrochlorideProduct ingredient for Tiletamine

Name
Tiletamine hydrochloride
Drug Entry
Tiletamine

This drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt form, exists as odorless white crystals.

Accession Number
DBSALT001704
Structure
Synonyms
Tiletamine HCl
UNII
99TAQ2QWJI
CAS Number
14176-50-2
Weight
Average: 259.795
Monoisotopic: 259.0797626
Chemical Formula
C12H18ClNOS
InChI Key
ZUYKJZQOPXDNOK-UHFFFAOYSA-N
InChI
InChI=1S/C12H17NOS.ClH/c1-2-13-12(11-7-5-9-15-11)8-4-3-6-10(12)14;/h5,7,9,13H,2-4,6,8H2,1H3;1H
IUPAC Name
2-(ethylamino)-2-(thiophen-2-yl)cyclohexan-1-one hydrochloride
SMILES
Cl.CCNC1(CCCCC1=O)C1=CC=CS1
ChemSpider
24715
ChEMBL
CHEMBL2105342
Predicted Properties
PropertyValueSource
Water Solubility0.0965 mg/mLALOGPS
logP2.58ALOGPS
logP3.01Chemaxon
logS-3.4ALOGPS
pKa (Strongest Acidic)19.71Chemaxon
pKa (Strongest Basic)7.91Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area29.1 Å2Chemaxon
Rotatable Bond Count3Chemaxon
Refractivity62.39 m3·mol-1Chemaxon
Polarizability24.65 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon