Cefadroxil monohydrateProduct ingredient for Cefadroxil
- Name
- Cefadroxil monohydrate
- Drug Entry
- Cefadroxil
Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
- Accession Number
- DBSALT001744
- Structure
Structure for Cefadroxil monohydrate (DBSALT001744)
- Synonyms
- Cefadroxil
- UNII
- 280111G160
- CAS Number
- 66592-87-8
- Weight
- Average: 381.4
Monoisotopic: 381.099456518 - Chemical Formula
- C16H19N3O6S
- InChI Key
- NBFNMSULHIODTC-CYJZLJNKSA-N
- InChI
- InChI=1S/C16H17N3O5S.H2O/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8;/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24);1H2/t10-,11-,15-;/m1./s1
- IUPAC Name
- (6R,7R)-7-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
- SMILES
- O.[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=C(O)C=C1)C(O)=O
- External Links
- Predicted Properties
Property Value Source Water Solubility 0.399 mg/mL ALOGPS logP 0.51 ALOGPS logP -2.4 Chemaxon logS -3 ALOGPS pKa (Strongest Acidic) 3.45 Chemaxon pKa (Strongest Basic) 7.22 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 132.96 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 90.95 m3·mol-1 Chemaxon Polarizability 35.86 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon