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Cefadroxil is a cephalosporin antibiotic used in the treatment of various bacterial infections, such as urinary tract infections, skin and skin structure infections, and tonsillitis. Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
- Mechanism
- Curator reviewed
Like all beta-lactam antibiotics, cefadroxil binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefadroxil interferes with an autolysin inhibitor.
- Primary indication
- For the treatment of the following infections (skin, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staphylococci and Streptococcus pyogenesCurator reviewed · 6 structured indications
- Formula / weight
- C16H17N3O5S · 363.388 g/mol (avg)
- First approval
- Canada, 1999 · United States, 1978
- Also known as
- Cephadroxil · D-Cefadroxil
Resolves to
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Which drugs share a target with Cefadroxil, and which of those have an active Phase 3 trial?