Nefopam hydrochlorideProduct ingredient for Nefopam
- Name
- Nefopam hydrochloride
- Drug Entry
- Nefopam
Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.
- Accession Number
- DBSALT002173
- Structure
Structure for Nefopam hydrochloride (DBSALT002173)
- Synonyms
- Nefopam HCl
- UNII
- 685J48E13W
- CAS Number
- 23327-57-3
- Weight
- Average: 289.8
Monoisotopic: 289.123342 - Chemical Formula
- C17H20ClNO
- InChI Key
- CNNVSINJDJNHQK-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18;/h2-10,17H,11-13H2,1H3;1H
- IUPAC Name
- 5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine hydrochloride
- SMILES
- Cl.CN1CCOC(C2=CC=CC=C2)C2=CC=CC=C2C1
- External Links
- ChemSpider
- 29555
- ChEMBL
- CHEMBL1407915
- Predicted Properties
Property Value Source Water Solubility 0.0803 mg/mL ALOGPS logP 3.16 ALOGPS logP 3.4 Chemaxon logS -3.5 ALOGPS pKa (Strongest Basic) 7.72 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 12.47 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 78.48 m3·mol-1 Chemaxon Polarizability 29.09 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon