Cefadroxil sodiumProduct ingredient for Cefadroxil

Name
Cefadroxil sodium
Drug Entry
Cefadroxil

Long-acting, broad-spectrum, water-soluble, cephalexin derivative.

Accession Number
DBSALT002304
Structure
Thumb
Synonyms
Not Available
UNII
SSZ6380I0I
CAS Number
42284-83-3
Weight
Average: 385.37
Monoisotopic: 385.07083608
Chemical Formula
C16H16N3NaO5S
InChI Key
GQOVFIUWRATNJC-CYJZLJNKSA-M
InChI
InChI=1S/C16H17N3O5S.Na/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8;/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24);/q;+1/p-1/t10-,11-,15-;/m1./s1
IUPAC Name
sodium (6R,7R)-7-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
SMILES
[Na+].CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)C1=CC=C(O)C=C1)C2=O)C([O-])=O
ChemSpider
34994042
Predicted Properties
PropertyValueSource
Water Solubility1.16 mg/mLALOGPS
logP0.31ALOGPS
logP-2.4ChemAxon
logS-2.5ALOGPS
pKa (Strongest Acidic)3.45ChemAxon
pKa (Strongest Basic)7.22ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area135.79 Å2ChemAxon
Rotatable Bond Count4ChemAxon
Refractivity101.79 m3·mol-1ChemAxon
Polarizability33.39 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon