Ethylmorphine hydrochlorideProduct ingredient for Ethylmorphine
- Name
- Ethylmorphine hydrochloride
- Drug Entry
- Ethylmorphine
A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products).
- Accession Number
- DBSALT002363
- Structure
Structure for Ethylmorphine hydrochloride (DBSALT002363)
- Synonyms
- Codethyline hydrochloride / Dionine hydrochloride / Ethylmorphine HCl / Ethylmorphine hydrochloride
- UNII
- MFM5450P3T
- CAS Number
- 125-30-4
- Weight
- Average: 349.86
Monoisotopic: 349.1444713 - Chemical Formula
- C19H24ClNO3
- InChI Key
- ZPPBASOODYCKDP-YZZSNFJZSA-N
- InChI
- InChI=1S/C19H23NO3.ClH/c1-3-22-15-7-4-11-10-13-12-5-6-14(21)18-19(12,8-9-20(13)2)16(11)17(15)23-18;/h4-7,12-14,18,21H,3,8-10H2,1-2H3;1H/t12-,13+,14-,18-,19-;/m0./s1
- IUPAC Name
- (1S,5R,13R,14S,17R)-10-ethoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15-tetraen-14-ol hydrochloride
- SMILES
- Cl.[H][C@@]12OC3=C(OCC)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1([H])C=C[C@@H]2O
- External Links
- ChemSpider
- 4514562
- ChEMBL
- CHEMBL2107695
- Predicted Properties
Property Value Source Water Solubility 0.835 mg/mL ALOGPS logP 1.72 ALOGPS logP 1.7 Chemaxon logS -2.6 ALOGPS pKa (Strongest Acidic) 13.78 Chemaxon pKa (Strongest Basic) 9.19 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 41.93 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 89.35 m3·mol-1 Chemaxon Polarizability 34.15 Å3 Chemaxon Number of Rings 5 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon