Sulbactam benzathineProduct ingredient for Sulbactam
- Name
- Sulbactam benzathine
- Drug Entry
- Sulbactam
Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus.6 When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.2
- Accession Number
- DBSALT002843
- Structure
Structure for Sulbactam benzathine (DBSALT002843)
- Synonyms
- Sulbactam benzathine
- External IDs
- CP-45,899-99 / CP-45899-99
- UNII
- 49MU89FVBV
- CAS Number
- 83031-43-0
- Weight
- Average: 706.83
Monoisotopic: 706.234235916 - Chemical Formula
- C32H42N4O10S2
- InChI Key
- YSEPFTSCLHUBNH-HFKSPEPWSA-N
- InChI
- InChI=1S/C16H20N2.2C8H11NO5S/c1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16;2*1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14/h1-10,17-18H,11-14H2;2*5-6H,3H2,1-2H3,(H,11,12)/t;2*5-,6+/m.11/s1
- IUPAC Name
- bis((2S,5R)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid); benzyl[2-(benzylamino)ethyl]amine
- SMILES
- [H][C@@]12CC(=O)N1[C@@]([H])(C(O)=O)C(C)(C)S2(=O)=O.[H][C@@]12CC(=O)N1[C@@]([H])(C(O)=O)C(C)(C)S2(=O)=O.C(CNCC1=CC=CC=C1)NCC1=CC=CC=C1
- External Links
- ChemSpider
- 10128656
- ChEMBL
- CHEMBL3989650
- Predicted Properties
Property Value Source Water Solubility 48.5 mg/mL ALOGPS logP -0.92 ALOGPS logP 2.89 Chemaxon logS -0.68 ALOGPS pKa (Strongest Basic) 8.95 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 24.06 Å2 Chemaxon Rotatable Bond Count 9 Chemaxon Refractivity 76.64 m3·mol-1 Chemaxon Polarizability 29.15 Å3 Chemaxon Number of Rings 6 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule Yes Chemaxon