Glucosamine hydrochlorideProduct ingredient for Glucosamine

Show full entry for Glucosamine
Name
Glucosamine hydrochloride
Drug Entry
Glucosamine

Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation.14 Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as a treatment for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and findings with unclear clinical significance during clinical trials.6,14 It is currently not approved as a prescription product by the FDA, but is widely available over the counter.

See full entry for Glucosamine
Accession Number
DBSALT002844
Structure
Similar Structures
Synonyms
Chitosamine HCl / Chitosamine hydrochloride / Glucosamine HCl
UNII
750W5330FY
CAS Number
66-84-2
Weight
Average: 215.63
Monoisotopic: 215.0560503
Chemical Formula
C6H14ClNO5
InChI Key
QKPLRMLTKYXDST-NSEZLWDYSA-N
InChI
InChI=1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1
IUPAC Name
(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol hydrochloride
SMILES
Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
ChemSpider
2005837
ChEMBL
CHEMBL1707007
Wikipedia
Glucosamine
Predicted Properties
PropertyValueSource
Water Solubility551.0 mg/mLALOGPS
logP-2.7ALOGPS
logP-3Chemaxon
logS0.49ALOGPS
pKa (Strongest Acidic)11.73Chemaxon
pKa (Strongest Basic)8.23Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count6Chemaxon
Hydrogen Donor Count5Chemaxon
Polar Surface Area116.17 Å2Chemaxon
Rotatable Bond Count1Chemaxon
Refractivity37.58 m3·mol-1Chemaxon
Polarizability16.87 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon