Phenindamine tartrateProduct ingredient for Phenindamine
- Name
- Phenindamine tartrate
- Drug Entry
- Phenindamine
Phenindamine is an antihistamine. Phenindamine blocks the effects of the naturally occurring chemical histamine in your body. Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. It is used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold. Symptoms of a phenindamine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.
- Accession Number
- DBSALT002846
- Structure
Structure for Phenindamine tartrate (DBSALT002846)
- Synonyms
- Phenindamine bitartrate / Phenindamine hydrogen tartrate / Phenindamine tartrate
- UNII
- 28725X3PV8
- CAS Number
- 569-59-5
- Weight
- Average: 411.454
Monoisotopic: 411.168187529 - Chemical Formula
- C23H25NO6
- InChI Key
- WFXURHIXPXVPGM-UHFFFAOYSA-N
- InChI
- InChI=1S/C19H19N.C4H6O6/c1-20-12-11-16-15-9-5-6-10-17(15)19(18(16)13-20)14-7-3-2-4-8-14;5-1(3(7)8)2(6)4(9)10/h2-10,19H,11-13H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)
- IUPAC Name
- 2,3-dihydroxybutanedioic acid; 2-methyl-9-phenyl-1H,2H,3H,4H,9H-indeno[2,1-c]pyridine
- SMILES
- OC(C(O)C(O)=O)C(O)=O.CN1CCC2=C(C1)C(C1=CC=CC=C21)C1=CC=CC=C1
- External Links
- ChemSpider
- 228552
- ChEMBL
- CHEMBL2107213
- Predicted Properties
Property Value Source Water Solubility 0.0277 mg/mL ALOGPS logP 4.04 ALOGPS logP 3.62 Chemaxon logS -4 ALOGPS pKa (Strongest Acidic) 16.62 Chemaxon pKa (Strongest Basic) 9 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 3.24 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 85.03 m3·mol-1 Chemaxon Polarizability 31.13 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon