Phenindamine is an antihistamine. Phenindamine blocks the effects of the naturally occurring chemical histamine in your body. Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor... The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
- Mechanism
- Curator reviewed
Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
- Primary indication
- Used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold.Curator reviewed
- Formula / weight
- C19H19N · 261.3609 g/mol (avg)
- Also known as
- Thephorin
- Code names
- NU-1504
Resolves to
ISFHAYSTHMVOJR-UHFFFAOYSA-NSMILESCN1CCC2=C(C1)C(C1=CC=CC=C21)C1=CC=CC=C1What you can answer from here — as of September 13, 2026
Which drugs share a target with Phenindamine, and which of those have an active Phase 3 trial?
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