Chlorprothixene hydrochlorideProduct ingredient for Chlorprothixene
- Name
- Chlorprothixene hydrochloride
- Drug Entry
- Chlorprothixene
Chlorprothixene is a typical antipsychotic drug of the thioxanthene (tricyclic) class. Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.
- Accession Number
- DBSALT002973
- Structure
Structure for Chlorprothixene hydrochloride (DBSALT002973)
- Synonyms
- Chlorprothixene HCl / Chlorprothixene hydrochloride / cis-Chlorprothixene hydrochloride
- UNII
- 268KCR965N
- CAS Number
- 6469-93-8
- Weight
- Average: 352.32
Monoisotopic: 351.0615262 - Chemical Formula
- C18H19Cl2NS
- InChI Key
- YWKRLOSRDGPEJR-KIUKIJHYSA-N
- InChI
- InChI=1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H/b14-7-;
- IUPAC Name
- {3-[(9Z)-2-chloro-9H-thioxanthen-9-ylidene]propyl}dimethylamine hydrochloride
- SMILES
- Cl.CN(C)CC\C=C1\C2=CC=CC=C2SC2=CC=C(Cl)C=C12
- External Links
- ChemSpider
- 4445622
- ChEMBL
- CHEMBL1256658
- Predicted Properties
Property Value Source Water Solubility 0.000366 mg/mL ALOGPS logP 5.42 ALOGPS logP 5.07 Chemaxon logS -5.9 ALOGPS pKa (Strongest Basic) 9.76 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 3.24 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 104.66 m3·mol-1 Chemaxon Polarizability 35.77 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon