Ciprofloxacin lactateProduct ingredient for Ciprofloxacin
- Name
- Ciprofloxacin lactate
- Drug Entry
- Ciprofloxacin
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics.9 It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.18,19,20,21,22,23,24,25,26
The first ciprofloxacin containing product was FDA approved on 22 October 1987.17
- Accession Number
- DBSALT002984
- Structure
Structure for Ciprofloxacin lactate (DBSALT002984)
- Synonyms
- Not Available
- UNII
- UEY6XFC224
- CAS Number
- 96186-80-0
- Weight
- Average: 421.425
Monoisotopic: 421.164913668 - Chemical Formula
- C20H24FN3O6
- InChI Key
- NRBJWZSFNGZBFQ-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H18FN3O3.C3H6O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;1-2(4)3(5)6/h7-10,19H,1-6H2,(H,23,24);2,4H,1H3,(H,5,6)
- IUPAC Name
- 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid; 2-hydroxypropanoic acid
- SMILES
- CC(O)C(O)=O.OC(=O)C1=CN(C2CC2)C2=C(C=C(F)C(=C2)N2CCNCC2)C1=O
- External Links
- ChemSpider
- 131779
- ChEMBL
- CHEMBL1077975
- Predicted Properties
Property Value Source Water Solubility 1.35 mg/mL ALOGPS logP -0.57 ALOGPS logP -0.86 Chemaxon logS -2.4 ALOGPS pKa (Strongest Acidic) 5.56 Chemaxon pKa (Strongest Basic) 8.77 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 72.88 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 87.94 m3·mol-1 Chemaxon Polarizability 33.39 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon