Tramazoline hydrochlorideProduct ingredient for Tramazoline

Show full entry for Tramazoline
Name
Tramazoline hydrochloride
Drug Entry
Tramazoline

Tramazoline is under investigation in clinical trial NCT01601509 (Nasal Tramazoline and Dexamethazone in Obstructive Sleep Apnea (OSA) Patients Tramazoline and).

See full entry for Tramazoline
Accession Number
DBSALT003102
Structure
Similar Structures
Synonyms
Tramazoline HCl / Tramazoline hydrochloride
External IDs
223-064-3
UNII
4DG710Q678
CAS Number
3715-90-0
Weight
Average: 251.76
Monoisotopic: 251.1189253
Chemical Formula
C13H18ClN3
InChI Key
RZOXEODOFNEZRS-UHFFFAOYSA-N
InChI
InChI=1S/C13H17N3.ClH/c1-2-6-11-10(4-1)5-3-7-12(11)16-13-14-8-9-15-13;/h3,5,7H,1-2,4,6,8-9H2,(H2,14,15,16);1H
IUPAC Name
N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride
SMILES
Cl.C1CN=C(NC2=CC=CC3=C2CCCC3)N1
ChemSpider
18349
ChEBI
32251
ChEMBL
CHEMBL2107640
Wikipedia
Tramazoline
Predicted Properties
PropertyValueSource
Water Solubility0.408 mg/mLALOGPS
logP2.27ALOGPS
logP2.73Chemaxon
logS-2.7ALOGPS
pKa (Strongest Basic)9.89Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area36.42 Å2Chemaxon
Rotatable Bond Count1Chemaxon
Refractivity66.96 m3·mol-1Chemaxon
Polarizability25.04 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon