Protirelin acetateProduct ingredient for Protirelin
- Name
- Protirelin acetate
- Drug Entry
- Protirelin
Protirelin is the pharmaceutically available synthetic analogue of the endogenous peptide thyrotropin-releasing hormone (TRH). It is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid Stimulating Hormone (TSH) and prolactin from the anterior pituitary.
Although not currently available in any FDA-approved product, protirelin is a component of the TRH Test where it is used to test the response of the anterior pituitary gland in conditions such as secondary hypothyroidism and acromegaly.
- Accession Number
- DBSALT003553
- Structure
Structure for Protirelin acetate (DBSALT003553)
- Synonyms
- TRF Acetate
- UNII
- Not Available
- CAS Number
- 120876-23-5
- Weight
- Average: 904.936
Monoisotopic: 904.403894531 - Chemical Formula
- C38H56N12O14
- InChI Key
- FCUSEANSBYKTPA-UHFFFAOYSA-N
- InChI
- InChI=1S/2C16H22N6O4.3C2H4O2/c2*17-14(24)12-2-1-5-22(12)16(26)11(6-9-7-18-8-19-9)21-15(25)10-3-4-13(23)20-10;3*1-2(3)4/h2*7-8,10-12H,1-6H2,(H2,17,24)(H,18,19)(H,20,23)(H,21,25);3*1H3,(H,3,4)
- IUPAC Name
- SMILES
- CC(O)=O.CC(O)=O.CC(O)=O.NC(=O)C1CCCN1C(=O)C(CC1=CN=CN1)NC(=O)C1CCC(=O)N1.NC(=O)C1CCCN1C(=O)C(CC1=CN=CN1)NC(=O)C1CCC(=O)N1
- External Links
- Not Available
- Predicted Properties
Property Value Source