Search
Atidarsagene autotemcel
go.drugbank.com/drugs/DB17538ApprovedInvestigationalAtidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced _ex vivo_ using … [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic
Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismSynonyms: Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) geneElapegademase
go.drugbank.com/drugs/DB14712Approvedgroup in alanine and lysine residues. … [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on October 5, 2018.[L4654,F1939]
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsSynonyms: ON N.ALPHA..1ALANINE AND N6 OF LYSINE RESIDUES WITH, AN AVERAGE OFAPPROXIMATELY 13 .OMEGA.MM-111
go.drugbank.com/drugs/DB17983InvestigationalMM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Categories: Amino Acids, Peptides, and ProteinsSynonyms: Antibody bispecific for erbb2 and erbb3Romilkimab
go.drugbank.com/drugs/DB16318InvestigationalRomilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Synonyms: Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13)Radotermin
go.drugbank.com/drugs/DB19127InvestigationalRadotermin is under investigation in clinical trial NCT01182337 (A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal Rhgdf-5 for the
Synonyms: Recombinant human growth and differentiation factor-5Afamitresgene autoleucel
go.drugbank.com/drugs/DB18592ApprovedInvestigational[L51114] The transduced T cells are expanded, washed, formulated into a suspension, and cryopreserved. … [L51114] MAGE-A4 is an intracellular cancer-testis antigen that is overexpressed by cancer cells in synovial sarcoma.
Synonyms: AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THEGinkgo biloba leaf oil
go.drugbank.com/drugs/DB14285InvestigationalGinkgo biloba leaf oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Common Ginkgo Leaf Oil, Ginkgo biloba leaf oilMucor circinelloides f. circinelloides
go.drugbank.com/drugs/DB15512ApprovedMucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Synonyms: Molds, rusts and smuts, mucor circinelloides f. circinelloidesFactor IX Complex (Human)
go.drugbank.com/drugs/DB11330ApprovedInvestigationalAlthough Factor IX Complex products contain many different coagulation components, Factor IX is the lead component for potency and efficacy, particularly when used for the treatment of bleeding associated … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated.
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsSynonyms: Coagulation factor IX, II, VII and X in combinationFluorescein
go.drugbank.com/drugs/DB00693ApprovedInvestigationalinjuries and corneal trauma. … A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal
Mixtures: Minims Lidocaine and Fluorescein, Fluorescein Sodium and Proparacaine HydrochlorideCategories: Indicators and Reagents