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Pasireotide
go.drugbank.com/drugs/DB06663ApprovedInvestigationalPasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Categories: Sex Hormones and InsulinsAlbiglutide
go.drugbank.com/drugs/DB09043ApprovedInvestigationalWithdrawnIt is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin. Albiglutide was approved on April 15, 2014 by the FDA.
Hyperglycemia during critical illness
go.drugbank.com/conditions/DBCOND0023008Ribosomal protein S6 kinase alpha-3
go.drugbank.com/bio_entities/BE0004876TargetHumansIn response to insulin, phosphorylates EIF4B, enhancing EIF4B affinity for the EIF3 complex and stimulating cap-dependent translation (PubMed:18508509, PubMed:18813292). … Upon insulin-derived signal, acts indirectly on the transcription regulation of several genes by phosphorylating GSK3B at 'Ser-9' and inhibiting its activity (PubMed:8250835).
Synonyms: Insulin-stimulated protein kinase 1Trastuzumab
go.drugbank.com/drugs/DB00072ApprovedInvestigationaldomain of the human epidermal growth factor receptor protein (HER2). … [L14015] It is used as a treatment of human epidermal growth factor receptor (HER)-2+ metastatic breast cancer, where there is a proven amplification of the HER-2 oncogene or over-expression of the HER
Categories: Antibodies, Monoclonal, Humanized, HER2 (Human Epidermal Growth Factor Receptor 2) inhibitorsDiabetic Ketoacidosis
go.drugbank.com/conditions/DBCOND0000979