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  1. Drug

    Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate

    go.drugbank.com/drugs/DB14701
    Experimental

    Synonyms: 5-Quinolinepropanoic acid, 8-hydroxy-alpha-(2-propyn-1-ylamino)-, ethyl ester, Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate
  2. Drug

    2',3'-dideoxy-3'-fluoro-urididine-5'-diphosphate

    go.drugbank.com/drugs/DB04068
    Experimental

    Synonyms: 2',3'-dideoxy-3'-fluoro-urididine-5'-diphosphate
  3. Drug

    2-(2-hydroxy-phenyl)-3H-benzoimidazole-5-carboxamidine

    go.drugbank.com/drugs/DB02287
    Experimental

    Synonyms: [2-(2-Hydroxyphenyl)-1H-benzimidazol-5-yl](imino)methanaminium
  4. Drug

    {[2-Amino-4-oxo-6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum

    go.drugbank.com/drugs/DB03983
    Experimental

    Synonyms: {[2-Amino-4-oxo-6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum, (Molybdopterin-S,S)-dioxo-thio-molybdenum(V)
  5. Drug

    Lenacapavir

    go.drugbank.com/drugs/DB15673
    ApprovedInvestigational

    [A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy _in vitro_, little to no cross-resistance with existing antiretroviral … [L42995] On December 22, 2022, it was also approved by the FDA.[L44473]

    Categories: Heterocyclic Compounds, 1-Ring, Human Immunodeficiency Virus 1 Capsid InhibitorSynonyms: -3-(TRIFLUOROMETHYL)-3B,4,4A,5-TETRAHYDRO-1H-CYCLOPR, DIFLUOROPHENYL)ETHYL)-5,5-DIFLUORO-3B,4,4A,5-TETRAHYD
  6. Drug

    Rifabutin

    go.drugbank.com/drugs/DB00615
    ApprovedInvestigational

    A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.

    Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesSynonyms: 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIV, 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin S
  7. Drug

    5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine

    go.drugbank.com/drugs/DB07141
    Experimental

    Synonyms: 5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
  8. Drug

    Oxibendazole

    go.drugbank.com/drugs/DB04910
    ExperimentalVet approved

    Oxibendazole is a polymerase inhibitor in phase III trials for the treatment of helminth intestinal infections.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: Methyl 5-n-propoxy-2-benzimidazole carbamate, Methyl 5-propoxy-2-benzimidazolecarbamate
  9. Drug

    Bufotenine

    go.drugbank.com/drugs/DB01445
    ExperimentalIllicit

    Bufotenin has been used as a tool in CNS studies and misused as a psychedelic. … A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics.

    Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsSynonyms: DM5-HT, 3-[2-(dimethylamino)ethyl]-5-indolol
  10. Drug

    Eniluracil

    go.drugbank.com/drugs/DB03516
    Investigational

    Eniluracil could improve 5-FU by increasing its effectiveness, reducing its side effects and/or making it orally available. … Eniluracil, which was previously under development by GlaxoSmithKline (GSK), is being developed by Adherex to enhance the therapeutic value and effectiveness of 5-fluorouracil (5-FU), one of the world’

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-Ethynyluracil