Bufotenine

DB01445ExperimentalIllicitSmall molecule

A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a... Bufotenin has been used as a tool in CNS studies and misused as a psychedelic.

Formula / weight: C₁₂H₁₆N₂O · 204.2682 g/mol (avg)
Also known as: Bufotenin · DM5-HT · N,N-dimethylserotonin

Resolves to

Compound

UNII0A31347TZKCAS487-93-4ChEMBLCHEMBL416526ChEBI3210PubChem10257KEGGC08299

Structure

InChIKeyVTTONGPRPXSUTJ-UHFFFAOYSA-NSMILESCN(C)CCC1=CNC2=C1C=C(O)C=C2

Targets

P47898HTR5AP34969HTR7P50406HTR6P28223HTR2AP28221HTR1D

What you can answer from here — as of September 23, 2026

5Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

677Drug interactionsStructured to mechanism, not free text

14+ReferencesStructured and connected to the statements they support

Which drugs share a target with Bufotenine, and which of those have an active Phase 3 trial?

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