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Mupirocin
go.drugbank.com/drugs/DB00410ApprovedInvestigationalVet approved[A178531,A178591] Mupirocin is commonly marketed under the brand name Bactroban. … Mupirocin, formerly termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents.
Synonyms: Pseudomonic acid AIsavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalResistance to isavuconazole has been associated with the mutation in the target gene CYP51 [FDA Label]. … Cross-resistance between isavuconazole and other azoles was also proposed although the clinical relevance is unclear [FDA Label].
Darbepoetin alfa
go.drugbank.com/drugs/DB00012ApprovedInvestigationalHuman erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Thonzylamine
go.drugbank.com/drugs/DB11235ApprovedThonzylamine is an antihistamine and anticholinergic drug. It is available as combination products with DB04837 or DB00388 for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.
Mixtures: Poly-Hist DMTechnetium Tc-99m tilmanocept
go.drugbank.com/drugs/DB09266ApprovedIt is a macromolecule consisting of multiple units of diethylenetriaminepentaacetic acid (DTPA) and mannose, each covalently attached to a 10 kDa dextran backbone [FDA Label]. … DTPA serves as a chelating agent for technetium Tc 99m to bind [FDA Label].
Vildagliptin
go.drugbank.com/drugs/DB04876ApprovedInvestigational[L32803] Vildagliptin is also available as Eucreas, a fixed-dose formulation with metformin for adults in who do not adequately glycemic control from monotherapy. … [A232488] Oral vildagliptin was approved by the European Medicines Agency in 2008 for the treatment of type II diabetes mellitus in adults as monotherapy or in combination with [metformin], a sulfonylurea
Mixtures: GLIMETAL-DP, Vildagliptin/Metformin 1A Pharma 50 mg/850 mg – FilmtablettenProducts: Vildagliptin 1A Pharma 50 mg - TablettenSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigational[A242412] In May 2015, the FDA approved sirolimus for the treatment of patients with lymphangioleiomyomatosis. … [A242372] In November 2000, the drug was recognized by the European Agency as an alternative to calcineurin antagonists for maintenance therapy with corticosteroids.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexZolpidem
go.drugbank.com/drugs/DB00425ApprovedInvestigationalZolpidem, also known as _Ambien_, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. … It is available in both immediate acting and extended release forms [FDA label], [F3802].
Synonyms: N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamideInternational brands: Stilnoct, StilnoxMeradimate
go.drugbank.com/drugs/DB11096ApprovedMeradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. … [T200] It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products.
Mixtures: Clinic A Retinol Vital Day Moist Lot Spf20, Herbal Day Creme SPF 15Heparin
go.drugbank.com/drugs/DB01109ApprovedInvestigationalUnfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. … It is a naturally occurring anticoagulant released from mast cells.
Products: HEPARIN NA BRA 25000IE, HEPARIN NA BRA 25000IE IIL