Thonzylamine is an antihistamine and anticholinergic drug. It is available as combination products with DB04837 or DB00388 for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or...
- Mechanism
- Curator reviewed · 2 references
Thonzylamine competes with histamine for binding to the H1 histamine receptor. Binding of histamine to this receptor stimulates vasodilation and increased vascular permeability leading to nasal congestion and runny nose. Histamine also produces itchiness by stimulating nerve endings which can result in sneezing. By blocking these effects, thonzylamine can reduce or eliminate symptoms of allergic rhinitis.
- Primary indication
- Thozylamine is indicated for use in the symptomatic control of allergic rhinitis or other upper respiratory allergic symptoms.Curator reviewed · 10 structured indications
- Formula / weight
- C16H22N4O · 286.379 g/mol (avg)
- Also known as
- neohetramine
- Brand names
Resolves to
GULNIHOSWFYMRN-UHFFFAOYSA-NSMILESCOC1=CC=C(CN(CCN(C)C)C2=NC=CC=N2)C=C1What you can answer from here — as of September 13, 2026
Which drugs share a target with Thonzylamine, and which of those have an active Phase 3 trial?
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