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Ioversol
go.drugbank.com/drugs/DB09134ApprovedInvestigational[L41780] Ioversol was approved by the FDA in 1989 and is currently indicated for computed tomographic (CT) imaging and contrast enhancement in peripheral arteriography, coronary arteriography, and left … Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N,N'-Bis (2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl) -glycolamido] -2,4,6-triiodoisophthalamideInfluenza B virus B/Brisbane/60/2008 antigen (propiolactone inactivated)
go.drugbank.com/drugs/DB11044ApprovedWithdrawnInactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
Mixtures: Medical Provider Single Use EZ Flu Shot Afluria 2016-2017, Medical Provider Single Use EZ Flu Shot Fluvirin 2016-2017Fomivirsen
go.drugbank.com/drugs/DB06759ApprovedWithdrawnIt is an antiviral agent that was used in the treatment of cytomegalovirus retinitis (CMV) in immunocompromised patients, including those with AIDS. … As a complementary nucleotide to the messenger RNA of the major immediate-early region proteins of human cytomegalovirus, it disrupts the replication of the virus through an antisense mechanism [L1428]
Categories: Compounds used in a research, industrial, or household settingCyclothiazide
go.drugbank.com/drugs/DB00606ApprovedThis results in an increase in potassium excretion via the sodium-potassium exchange mechanism. … As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water.
Amrinone
go.drugbank.com/drugs/DB01427ApprovedWithdrawnIt is used in the treatment of congestive heart failure.
Categories: Compounds used in a research, industrial, or household settingPenicillium italicum
go.drugbank.com/drugs/DB10811ApprovedPenicillium italicum extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureTarlatamab
go.drugbank.com/drugs/DB17256ApprovedInvestigational[L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed … Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer.
Imlunestrant
go.drugbank.com/drugs/DB19043ApprovedInvestigational[L54046] Imlunestrant works by antagonizing ER transcriptional activity and, by forming an unstable drug-receptor complex, promotes ER degradation via the ubiquitin-proteasome pathway. … [A256828] In clinical trials, imlunestrant has been investigated as monotherapy and in combination with other drugs in breast cancer patients.[A256828]
Sacituzumab govitecan
go.drugbank.com/drugs/DB12893ApprovedInvestigational[A193653] Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a recent advance in cancer treatment. … Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents.
Atractylodes lancea root oil
go.drugbank.com/drugs/DB14338ApprovedAtractylodes lancea root oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: OHUI Sun Science Sun Block EX plus Beige