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Tetradecyl hydrogen sulfate (ester)
go.drugbank.com/drugs/DB11328ApprovedSodium tetradecyl sulfate has been widely used since the 1950s, and in 1978 the first successful report of injecting a 1% solution into spider angiomas in 144 patients was made. … Sodium tetradecyl sulfate is an anionic surface-active agent which is used for its wetting properties in the industry and is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids
alpha-Tocopherol succinate
go.drugbank.com/drugs/DB14001ApprovedNutraceuticalVet approvedNevertheless, vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals. … Vitamin E itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement.
Mixtures: Dry Form Vitamin E 400iu With Selenium 100mcgFluocinolone acetonide
go.drugbank.com/drugs/DB00591ApprovedInvestigationalVet approved[T357] It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices. … [T358] This type of device containing fluocinolone acetonide was developed by Taro Pharmaceuticals and approved by FDA in May 2016.[L4676]
Cefroxadine
go.drugbank.com/drugs/DB11367ApprovedWithdrawnAs part of its drug class, it shares structural properties to [cefalexin] as well as its activity spectrum. It was used in Italy but has since been withdrawn.
Cannabidiol
go.drugbank.com/drugs/DB09061ApprovedInvestigationalEpidiolex was granted Orphan Drug designation as well as Fast Track Approval from the FDA for further study in these hard to treat conditions. … CBD is currently available in Canada within a 1:1 formulation with tetrahydrocannbinol (THC) (as the formulation known as "nabiximols") as the brand name product Sativex.
Diatrizoate
go.drugbank.com/drugs/DB00271ApprovedVet approvedAs diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Mixtures: Peritrast 180mg Jod/ml - Lösung zur parenteralen AnwendungSynonyms: 3,5-Bis(acetylamino)-2,4,6-triiodobenzoic acidOsimertinib
go.drugbank.com/drugs/DB09330ApprovedInvestigational[A7928] Development of third-generation EGFR-TKIs, such as osimertinib, has been in response to altered tumour resistance patterns following treatment and toxic side effects that impact patient quality … testing and which has progressed following therapy with a first-generation EGFR tyrosine kinase inhibitor.
Glycyrrhizic acid
go.drugbank.com/drugs/DB13751ApprovedInvestigational[A33062] From January 2014, glycyrrhizic acid as part of the licorice extract was approved by the FDA as an existing food sweetener. … [T204] Glycyrrhizic acid has been developed in Japan and China as a hepatoprotective drug in cases of chronic hepatitis.
Oral Malodor (Halitosis)
go.drugbank.com/conditions/DBCOND0035973Drugs: DequaliniumSynonyms: Bad Breath, Bad breath - halitosisAdagrasib
go.drugbank.com/drugs/DB15568ApprovedInvestigational[A254941] However, the development of KRAS inhibitors has been challenging due to their high affinity for guanosine triphosphate (GTP) and guanosine diphosphate (GDP), as well as the lack of a clear binding … KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations.
Categories: RAS GTPase Inhibitors