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Filgotinib
go.drugbank.com/drugs/DB14845ApprovedInvestigational[A189165] Filgotinib is currently reserved for patients who cannot tolerate DMARDs, or who have been unable to achieve remission in response to one or more DMARDs.[L16616] … Rheumatoid arthritis (RA) is a chronic, autoimmune, systemic, and inflammatory disease that causes synovial joint symptoms and can limit range of motion in severe cases.
Tamoxifen
go.drugbank.com/drugs/DB00675ApprovedInvestigational[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments. … Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.
Categories: UGT2B7 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: TAMOXIFEN AL 20, TAMOXIFEN AL 30Aflibercept
go.drugbank.com/drugs/DB08885ApprovedInvestigational[A261130] Structurally, Aflibercept is a dimeric glycoprotein with a protein molecular weight of 96.9 kilo Daltons (kDa). … [A261276] It contains approximately 15% glycosylation to give a total molecular weight of 115 kDa.
Products: Zaltrap 25mg/ml Concentrate for Solution for Infusion, ZALTRAP CONCENTRATE FOR SOLUTION FOR INFUSION 25 MG/MLAvalglucosidase alfa
go.drugbank.com/drugs/DB16099ApprovedInvestigationalAvalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase … GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions.
Products: NEXVIAZYME 100mg Powder for Concentrate for Solution for InfusionPrasterone
go.drugbank.com/drugs/DB01708ApprovedInvestigationalNutraceuticalIn the United States, DHEA or DHEAS have been advertised with claims that they may be beneficial for a wide variety of ailments. … In Canada, a prescription is required to buy DHEA.
Categories: Anabolic Agents for Systemic UseEteplirsen
go.drugbank.com/drugs/DB06014ApprovedInvestigationalEteplirsen was first approved by the FDA in September 2016 for the treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation of the DMD gene, which codes for dystrophin, that … Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer.
Synonyms: (P-deoxy-P-(dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(C-m5U-C-C-A-A-C-A-m5U-C-A-A-G-G-A-A-G-A-m5U-G-G-C-A-m5U-m5U-m5U-C-m5U-A-G),5'-(P-(4-((2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)carbonylCategories: Compounds used in a research, industrial, or household settingSynthetic Conjugated Estrogens, B
go.drugbank.com/drugs/DB09318ApprovedHowever, once a woman stops ovulating there is a sharp decline in the production of progesterone and estradiol by the ovaries and a consequent fluctuation in LH and FSH due to a lack of feedback control … There is currently no generic form of CEEs available as a detailed analytical characterization of the active ingredients or of their estrogenic activity is not available at this time.
Methyl nicotinate
go.drugbank.com/drugs/DB13882ApprovedMethyl nicotinate is the methyl ester of [DB00627] that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. … The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation.
Mixtures: Arthricare for Women Nighttime, Arthricare for Women Multi-actionHuman papillomavirus type 33 L1 capsid protein antigen
go.drugbank.com/drugs/DB10311ApprovedInvestigationalHuman papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 33.
Synonyms: L1 protein, Human papillomavirus type 33 Vaccine, Human papillomavirus type 33 L1 capsid protein antigenMixtures: GARDASIL 9 SUSPENSION FOR INJECTIONHuman papillomavirus type 45 L1 capsid protein antigen
go.drugbank.com/drugs/DB10312ApprovedInvestigationalHuman papillomavirus type 45 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 45.
Synonyms: L1 protein, Human papillomavirus type 45 Vaccine, Human papillomavirus type 45 L1 capsid protein antigenMixtures: GARDASIL 9 SUSPENSION FOR INJECTION