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Displaying results 101 - 110 of 1901 in total
  1. Drug

    Sotatercept

    go.drugbank.com/drugs/DB12118
    ApprovedInvestigational

    [L50351] On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension (PAH). … It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain.

    Synonyms: ACTIVIN RECEPTOR TYPE IIA (SYNTHETIC HUMAN EXTRACELLULAR DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER, (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-
  2. Drug

    RTL-1000

    go.drugbank.com/drugs/DB17946
    Investigational

    RTL-1000 is a recombinant T-Cell receptor ligand being investigated for the treatment of multiple sclerosis.

    Synonyms: Recombinant t-cell receptor ligand rtl-1000, Rtl-1000 (recombinant t-cell receptor ligand)
  3. Drug

    Icanbelimod

    go.drugbank.com/drugs/DB21572
    Experimental

    Icanbelimod is a small molecule drug. The usage of the INN stem '-imod' in the name indicates that Icanbelimod is a immunomodulator, both stimulant/suppressive and stimulant. Icanbelimod has a monoisotopic molecular weight of 409.18 Da.

    Synonyms: S1p receptor agonist 1
  4. Drug

    KRN-633

    go.drugbank.com/drugs/DB33594
    Experimental

    Synonyms: Vegf receptor tyrosine kinase inhibitor iii
  5. Drug

    Lipoic acid

    go.drugbank.com/drugs/DB00166
    ApprovedInvestigationalNutraceutical

    A vitamin-like antioxidant.

    Products: ALPHA LIPOGAMMA 600MG FTA
  6. Drug

    Ropinirole

    go.drugbank.com/drugs/DB00268
    ApprovedInvestigational

    Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. … Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547].

    Categories: Nonergot-derivative Dopamine Receptor AgonistsProducts: ROPINIROL HEUMANN 5MG FTA
  7. Drug

    4A10

    go.drugbank.com/drugs/DB18292
    Experimental

    Synonyms: Anti-interleukin-7 Receptor α Monoclonal antibody
  8. Drug

    Prolactin G129R

    go.drugbank.com/drugs/DB18431
    Investigational

    Synonyms: Prolactin receptor antagonist (Prolactin G129R)
  9. Drug

    Cetirizine

    go.drugbank.com/drugs/DB00341
    ApprovedInvestigational

    Cetirizine is one of the first second-generation H1 antihistamines (SGAHs) formulated to selectively inhibit the H1 receptor without sedating effects [A175054].

    Products: CETIRIZIN HEU 10MG FTA, CETIRIZIN PUREN 10MG FTA
  10. Drug

    Bicalutamide

    go.drugbank.com/drugs/DB01128
    ApprovedInvestigational

    Bicalutamide binds to the androgen receptor.

    Categories: Androgen Receptor Antagonists, Androgen Receptor InhibitorsProducts: CASODEX 50MG FTA, BICALUTAMID TEVA 150MG FTA