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Displaying results 101 - 110 of 6073 in total
  1. Drug

    Coagulation Factor IX Human

    go.drugbank.com/drugs/DB13152
    ApprovedInvestigational

    Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.

    Mixtures: OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU, BERIPLEX P/N 500 POWDER FOR SOLUTION FOR INJECTIONProducts: IMMUNINE 120IU/ML Powder and solvent for solution for injection or infusion, REPLENINE-VF 500 FOR INJECTION
  2. Drug

    Paclitaxel

    go.drugbank.com/drugs/DB01229
    ApprovedInvestigationalVet approved

    It is available as an intravenous solution for injection and the newer formulation contains albumin-bound paclitaxel marketed under the brand name Abraxane. … Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel

    Synonyms: Paclitaxel protein-bound particles for injection suspensionProducts: Aclipak Concentrate for Solution for Infusion 6mg/ ml, FONKOPAC CONCENTRATE FOR SOLUTION FOR INFUSION 6MG/ML
  3. Drug

    Ranibizumab

    go.drugbank.com/drugs/DB01270
    ApprovedInvestigational

    In order to improve drug delivery to the target organ, ranibizumab is available for intravitreal use. … ranibizumab first began after [bevacizumab], another anti-VEGF anticancer drug, was discovered to inhibit neovascularization and used in the off-label treatment of neovascular age-related macular degeneration for

    Products: Lucentis 10mg/ml Solution for Injection, ACCENTRIX 10MG/ML SOLUTION FOR INJECTION
  4. Drug

    Gemtuzumab ozogamicin

    go.drugbank.com/drugs/DB00056
    ApprovedInvestigational

    candidates for cytotoxic chemotherapy [A98]. … It is also indicated for the treatment of patients aged 2 years and older with CD33-positive AML who have experienced a relapse or who have not responded to initial treatment (refractory) [L941].

    Products: MYLOTARG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 5MG/VIAL
  5. Drug

    Simoctocog alfa

    go.drugbank.com/drugs/DB09108
    Approved

    As patients with haemophilia A are predisposed to episodes of recurrent bleeding [L1115], simoctocog alfa can be administered for the treatment or prevention of bleeding such as prior to surgical procedures

    Products: Nuwiq 250IU Powder for Solution for Injection, Nuwiq 500IU Powder for Solution for Injection
  6. Drug

    Denosumab

    go.drugbank.com/drugs/DB06643
    ApprovedInvestigational

    for fracture receiving adjuvant aromatase inhibitor therapy for breast cancer in September 2011 and in men with osteoporosis at high risk for fracture in September 2012. … It further received additional indication approval to increase bone mass in men at high risk for fracture receiving androgen deprivation therapy for non-metastatic prostate cancer and women at high risk

    Categories: Drugs for Treatment of Bone DiseasesProducts: XGEVA 120mg Solution for Injection, XGEVA Solution for Injection 120 mg/vial
  7. Drug

    Daratumumab

    go.drugbank.com/drugs/DB09331
    ApprovedInvestigational

    [L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and light chain (AL) amyloidosis in combination with other drugs. … [L13290,L13296] A subcutaneous formulation of daratumumab co-formulated with hyaluronidase-fihj is also approved for the treatment of adults with multiple myeloma.

    Products: DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 400MG/20ML, DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/5ML
  8. Drug

    Inclisiran

    go.drugbank.com/drugs/DB14901
    ApprovedInvestigational

    [A225953,A225958] On December 11, 2020, the European Commission (EC) granted authorization for marketing inclisiran as the first and only approved siRNA for the treatment of adults with primary hypercholesterolemia … [L28178] Inclisiran was later approved by the FDA on December 22, 2021, for the treatment of heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease in adults

    Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaProducts: LEQVIO SOLUTION FOR INJECTION IN PREFILLED SYRINGE 284 MG/1.5 ML, Sybrava 284mg/1.5ml Solution for Injection in Pre-filled Syringe
  9. Drug

    Tolfenamic acid

    go.drugbank.com/drugs/DB09216
    Approved

    By the European Medicine Agency, it was granted in 2016 with the status of orphan for the treatment of supranuclear palsy.[L1291] … It is used in the UK as a treatment for migraine under the name of Clotam.[L1292] In the US, it presents a Status class I by the FDA.

    Products: TOLFEDINE 4% W/V SOLUTION FOR INJECTION FOR DOGS AND CATS, Tolfine Solution for Injection 4.0% W/V
  10. Drug

    Acetazolamide

    go.drugbank.com/drugs/DB00819
    ApprovedInvestigationalVet approved

    One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizur...

    Products: Acetazolamide 500mg Powder for Solution for Injection, DIAMOX Sodium 500mg Powder for Solution for Injection