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Displaying results 101 - 110 of 10000 in total
  1. Drug

    beta-Sitosterol

    go.drugbank.com/drugs/DB14038
    Investigational

    Active fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity.

    Synonyms: (24R)-ethylcholest-5-en-3β-ol, (24R)-Stigmast-5-en-3beta-olMixtures: Mi-Omega NF
  2. Drug

    Ginsenoside Rd

    go.drugbank.com/drugs/DB19256
    Investigational

    Ginsenoside Rd is under investigation in clinical trial NCT00815763 (Efficacy and Safety of Ginsenoside-rd for Acute Ischemic Stroke).

    Synonyms: .)-20-(.beta.-d-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-o-.beta.-d-glucopyranosyl-
  3. Drug

    3-(1H-tetrazol-5-ylamino)cyclohex-2-en-1-one

    go.drugbank.com/drugs/DB07865
    Experimental

    Synonyms: 3-(1H-tetrazol-5-ylamino)cyclohex-2-en-1-one
  4. Drug

    Itruvone

    go.drugbank.com/drugs/DB21543
    Investigational

    Itruvone is under investigation in clinical trial NCT02322086 (A Phase 2 Study of Cellular and Immunologic Changes in the Skin of Subjects Receiving PH-10).

    Synonyms: Pregn-4-en-20-yn-3-one
  5. Drug

    Olesoxime

    go.drugbank.com/drugs/DB05185
    Investigational

    Olesoxime is a cholesterol-like small molecule that has demonstrated a remarkable neuroprotective profile in a battery of both in vitro and in vivo preclinical models. … For example, it has demonstrated the ability to prevent neurodegeneration, enhance nerve function and accelerate neuroregeneration following nerve trauma.[A3282,A253233]

    Synonyms: (EZ)-N-(CHOLEST-4-EN-3-YLIDENE)HYDROXYLAMINE, cholest-4-en-3-one, oxime
  6. Drug

    Solasodine

    go.drugbank.com/drugs/DB18813
    Investigational

    Synonyms: (3.beta.,22.alpha.,25r)-spirosol-5-en-3-ol, Spirosol-5-en-3-ol, (3.beta.,22.alpha.,25r)-
  7. Drug

    Venetoclax

    go.drugbank.com/drugs/DB11581
    ApprovedInvestigational

    Venetoclax is approximately 10 times more potent than navitoclax with regard to induction of apoptosis in CLL cells [A40022]. … Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process [A18565], [A18566].

    Categories: BCL-2 Inhibitor, Heterocyclic Compounds, 2-RingSynonyms: 4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro-2H-pyran-4-ylmethyl)amino)phenyl)sulfonyl)-2-(1H-pyrrolo(2,3-b)pyridin-5-yloxy)benzamide, 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
  8. Drug

    18-methyl-19-nortestosterone

    go.drugbank.com/drugs/DB01543
    ExperimentalIllicit

    Synonyms: 13beta-ethyl-17beta-hydroxygon-4-en-3-one
  9. Drug

    Pregnenolone acetate

    go.drugbank.com/drugs/DB14626
    Investigational

    Synonyms: 3beta-Hydroxypregn-5-en-20-one acetate
  10. Drug

    Sotatercept

    go.drugbank.com/drugs/DB12118
    ApprovedInvestigational

    [A263481] Sotatercept was approved by the European Commission on August 26, 2024.[L51549] … [L50351] On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension (PAH).

    Categories: Immunoglobulin GSynonyms: (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-, (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-