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Displaying results 1091 - 1100 of 4860 in total
  1. Drug

    Hepatitis B Vaccine (Recombinant)

    go.drugbank.com/drugs/DB11627
    ApprovedInvestigationalWithdrawn

    It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. … It is estimated that the reservoir of persistent hepatitis B surface antigen carriers amounts to 350 million people worldwide.

  2. Drug

    Talimogene laherparepvec

    go.drugbank.com/drugs/DB13896
    ApprovedInvestigational

    It specifically replicates within tumor cells and causes lysis. It was approved by the FDA in 2015 under the market name Imlygic. … In general, talimogene laherparepvec has been modified so that it can infect and multiply inside melanoma cells [L2221].

  3. Drug

    Prussian blue

    go.drugbank.com/drugs/DB06783
    Approved

    It contains ferric hexacyanoferrate(II) in a cubic lattice crystal structure. … It is insoluble in water but also tends to form a colloid thus can exist in either colloidal or water-soluble form, and an insoluble form.

  4. Drug

    Benralizumab

    go.drugbank.com/drugs/DB12023
    ApprovedInvestigational

    It is an afucosylated IgG which gives it high affinity for the FcγRIIIα receptor in natural killer cells, macrophages and neutrophils. … [A31294] It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R, thus blocking signal transduction.

  5. Drug

    Voretigene neparvovec

    go.drugbank.com/drugs/DB13932
    ApprovedInvestigational

    It is not pathogenic and it causes a very mild immune response.

  6. Drug

    Mirabegron

    go.drugbank.com/drugs/DB08893
    ApprovedInvestigational

    It is unique amongst overactive bladder treatment options in that, unlike other treatments such as [solifenacin] and [darifenacin], it lacks significant antimuscarinic activity,[A232553] which is responsible … Mirabegron has a comparatively favorable adverse effect profile as compared to other available treatment options, and its complementary mechanism to the antimuscarinics that came before it allows for its

  7. Drug

    Ustilago tritici

    go.drugbank.com/drugs/DB10444
    Approved

    Ustilago tritici is a fungus which can provoke allergic reactions. Ustilago tritici extract is used in allergenic testing.

    Mixtures: Grain Smut Mix, Grain Smut Mix
  8. Drug

    Anthralin

    go.drugbank.com/drugs/DB11157
    Approved

    It is a main active ingredient in topical skin formulations for the treatment of psoriasis. Various formulations of the drug are available, including solutions, foams, and shampoos [L1979]. … It is important to consider that the drug is relatively innocuous, yet effective, and systemic side effects have not been observed with this anthralin, in contrast to a wide variety of systemic and topical

  9. Drug

    Difluprednate

    go.drugbank.com/drugs/DB06781
    ApprovedInvestigational

    It is indicated for treatment of endogenous anterior uveiti. … It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate.

  10. Drug

    Follitropin

    go.drugbank.com/drugs/DB00066
    ApprovedInvestigational

    The nomenclature “beta” differentiates it from another recombinant human FSH product that was marketed earlier as follitropin alpha. … Given by subcutaneous injection, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility.