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Displaying results 1091 - 1100 of 7283 in total
  1. Drug

    Mecasermin

    go.drugbank.com/drugs/DB01277
    ApprovedInvestigational

    Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons.

  2. Drug

    Aminothiazole

    go.drugbank.com/drugs/DB20033
    Experimental

    Aminothiazole is a small molecule drug. Aminothiazole has a monoisotopic molecular weight of 100.01 Da.

    Categories: DNA Helicases, antagonists & inhibitors
  3. Drug

    Crotalus scutulatus antivenin

    go.drugbank.com/drugs/DB13891
    Approved

    Specimens with type A venom, which cause a different pattern of injury than other rattlesnakes, have been reported in southern California, Nevada, Utah, Arizona, Texas, and New Mexico [L2856]. … CROFAB (crotalidae polyvalent immune fab (ovine))is a sheep-derived antivenin used for the management of adult and pediatric patients with North American crotalid envenomation [FDA label], which includes

  4. Drug

    Palivizumab

    go.drugbank.com/drugs/DB00110
    ApprovedInvestigational

    Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). … Palivizumab is composed of to heavy chains (50.6 kDa each) and two light chains (27.6 kDa each), contains 1-2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF)

  5. Drug

    Decitabine

    go.drugbank.com/drugs/DB01262
    ApprovedInvestigational

    [A215082, A215092] Among treatment options, nucleoside analogues such as decitabine and [azacitidine] integrate into cellular DNA and inhibit the action of DNA methyltransferases, leading to global hypomethylation … Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.

    Synonyms: DAC, 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one
  6. Drug

    Narsoplimab

    go.drugbank.com/drugs/DB16418
    ApprovedInvestigational

    [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as a treatment for hematopoietic stem cell transplant-associated TMA (HSCT-TMA/TA-TMA) and IgA nephropathy … [A241030] Evidence increasingly points to a role for the complement system in TMA.

  7. Drug

    Enalapril

    go.drugbank.com/drugs/DB00584
    ApprovedInvestigationalVet approved

    It was developed from a targeted research programmed using molecular modelling. … It is also found in a combination product containing [hydrochlorothiazide] that is used for the management of hypertension.

    Mixtures: ENALAPRIL 1A PL 20/6MG, ENALAPRIL 1A PL 20/6MGProducts: ENALAPRIL 5 1A PHARMA, ENALAPRIL 10 1A PHARMA
  8. Drug

    Elvitegravir

    go.drugbank.com/drugs/DB09101
    ApprovedInvestigational

    It was FDA approved on August 27, 2012. On September 24, 2014, the FDA approved the single pill form of elvitegravir. … Because integrase is necessary for viral replication, inhibition prevents the integration of HIV-1 DNA into the host genome and thereby blocks the formation of the HIV-1 provirus and resulting propagation

  9. Drug

    Magnesium acetate

    go.drugbank.com/drugs/DB13996
    Approved

    Synonyms: acetato de magnesio, Magnesium di(acetate)Mixtures: ELETTROLITICA BILANCIATA DI MANTENIMENTO CON GLUCOSIO BAXTER, ELETTROLITICA BILANCIATA DI MANTENIMENTO CON GLUCOSIO BAXTER
  10. Drug

    Istradefylline

    go.drugbank.com/drugs/DB11757
    ApprovedInvestigational

    [A184067] Unlike standard dopaminergic therapies for Parkinson's, Istradefylline targets adenosine A<sub>2A</sub> receptors in the basal ganglia. … [A184067] Istradefylline was granted FDA approval on 27 August 2019.[L8213]