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Nortriptyline
go.drugbank.com/drugs/DB00540ApprovedInvestigationalNortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Synonyms: 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamineCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT1 Receptor AntagonistsChlorphenoxamine
go.drugbank.com/drugs/DB09007ApprovedWithdrawnIt is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.
Mixtures: SISTRAL C DRAJE , 20 ADETProducts: SISTRAL 10 MG/ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 6 ADET, SYSTRAL JEL, 20 GAntihemophilic factor, human recombinant
go.drugbank.com/drugs/DB00025ApprovedInvestigationalHuman recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Mixtures: FANHDI 500 U.I., FANHDI® 1500 U.I.International brands: Monarc-MEtofenamate
go.drugbank.com/drugs/DB08984InvestigationalEtofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID).
Mixtures: HOTFİX 100 MG/G + 10 MG/G KREM , 50 GRAM, THERMO RHEUMON 100 MG/G + 10 MG/G KREM, 50 GProducts: ETOVER 100 MG / ML SPREY, 50 ML, RHEUMON 100 MG/ML SPREY, 50 MLPentoxyverine
go.drugbank.com/drugs/DB11186ApprovedWithdrawn[L43942] Other forms of pentoxyverine citrate continue to be marketed. … Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate.
Mixtures: GAYABEN 150 ML SURUPProducts: PENTOXYVERIN AL 1.35 MG/ML, Mucomat Hustenstiller 2,13 mg/ml Lösung zum EinnehmenGemfibrozil
go.drugbank.com/drugs/DB01241ApprovedInvestigationalGemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias. … [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications.
Synonyms: 2,2-Dimethyl-5-(2,5-xylyloxy)valeriansäure, 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acidCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsLisdexamfetamine
go.drugbank.com/drugs/DB01255ApprovedInvestigational[L48285] Lisdexamfetamine works to treat attention deficit hyperactivity disorder and binge eating disorder [A2230] by blocking dopamine and norepinephrine reuptake and increasing their levels in the extraneuronal … Lisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine,[A40246] covalently attached to the naturally occurring amino acid L-lysine.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: VYVANSE CAPSULES 60 mg, VYVANSE® 60 MG CAPSULASBenznidazole
go.drugbank.com/drugs/DB11989ApprovedInvestigationalBenznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: ABALEA ®100 MGAluminum acetate
go.drugbank.com/drugs/DB14518ApprovedInvestigationalMixtures: Zo Medical Zo Post Procedure Recovery SystemProducts: ACETATO DE ALUMINIO 15 MG/100 ML SOLUCION TOPICA, ACETATO DE ALUMINIO 0.118G/100 MLSotorasib
go.drugbank.com/drugs/DB15569ApprovedInvestigationalSotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen. … [L34288] This mutation makes up >50% of all KRAS mutations.[A187550] Mutant KRAS discovered in 1982 but was not considered a druggable target until the mid-2010s.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: LUMAKRAS 120 MG FİLM KAPLI TABLET, 240 ADET