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Displaying results 1121 - 1130 of 10000 in total
  1. Drug

    Progesterone

    go.drugbank.com/drugs/DB00396
    ApprovedInvestigationalVet approved

    Pharmaceutical progesterone is made from a plant source as a starting material and is chemically identical to progesterone of human ovarian origin [FDA label]. … A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609].

    Synonyms: (S)-4-Pregnene-3,20-dione, (S)-Pregn-4-en-3,20-dioneMixtures: SYNERGAL® DOBLE, Minoxidil 7% / Progesterone 0.1%
  2. Drug

    Colloidal oatmeal

    go.drugbank.com/drugs/DB11286
    ApprovedNutraceutical

    Colloidal oatmeal is a FDA-approved skin protectant that temporarily protects and helps relieve minor skin irritation and itching due to rashes, eczema, poison ivy, oak, sumac, or insect bites. … It is available in topical products as a skin soothing agent.

    Mixtures: Pediadermics Eczema 3, 5% Oat Facial CleanserProducts: A Bit Hippy, TMC-A Hair Tonic
  3. Drug

    Frovatriptan

    go.drugbank.com/drugs/DB00998
    Approved

    Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation.

    Categories: Serotonin 5-HT1 Receptor Agonists, Selective Serotonin 5-HT1 Receptor AgonistsProducts: EUMITAN 2.5MG FTA, NEWART 2.5 MG TABLET, 3 ADET
  4. Target

    Atrial natriuretic peptide receptor 1

    go.drugbank.com/bio_entities/BE0000556
    TargetHumans

    Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis (PubMed:39543315).

    Polypeptides: Atrial natriuretic peptide receptor 1Synonyms: Atrial natriuretic peptide receptor type A, ANP-A
  5. Drug

    Tagraxofusp

    go.drugbank.com/drugs/DB14731
    ApprovedInvestigational

    Tagraxofusp is a CD123-directed cytotoxin. … [A253762, A253887, L43702] Tagraxofusp received its first global approval by the FDA on December 21, 2018 as the first FDA-approved treatment for blastic plasmacytoid dendritic cell neoplasm, which is

    Synonyms: Diphtheria toxin-il-3 fusion protein targeting IL-3 receptor
  6. Target

    Nucleoside diphosphokinase

    go.drugbank.com/bio_entities/BE0009626
    EnzymeHumans

    Phosphorylates the GNB1 subunit of heterotrimeric G proteins at 'His-266', generating a high-energy phosphate group that promotes GTP formation and enables receptor-independent activation of heterotrimeric … Catalyzes the transfer of a gamma-phosphoryl group from a nucleoside triphosphate, mainly ATP, to a nucleoside diphosphate via a ping-pong mechanism involving a phosphohistidine intermediate, therefore

    Polypeptides: Nucleoside diphosphate kinase ASynonyms: NDPK A, NDP kinase A
  7. Drug

    Piracetam

    go.drugbank.com/drugs/DB09210
    ApprovedWithdrawn

    Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. … It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA).

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingProducts: PIRACETAM RATIO 800MG FTA, PIRACETAM - CT 1200MG FTA
  8. Drug

    Escitalopram

    go.drugbank.com/drugs/DB01175
    ApprovedInvestigational

    Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram]. … that the R-enantiomer of racemic citalopram actively dampens the activity of escitalopram rather than existing simply as an inactive enantiomer.

    Synonyms: (S)-Citalopram, S(+)-CitalopramCategories: Monoamine Oxidase A Substrates, Cytochrome P-450 Substrates
  9. Drug

    Methylprednisolone

    go.drugbank.com/drugs/DB00959
    ApprovedInvestigationalVet approved

    Methylprednisolone is a [prednisolone] derivative glucocorticoid with higher potency than [prednisone].[A188811] It was first described in the literature in the late 1950s. … [A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957.

    Mixtures: P-Care D80, P-Care D40Categories: Compounds used in a research, industrial, or household setting, Corticosteroid Hormone Receptor Agonists
  10. Drug

    Exemestane

    go.drugbank.com/drugs/DB00990
    ApprovedInvestigational

    Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal

    Synonyms: 6-methyleneandrosta-1,4-diene-3,17-dioneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates