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Phenylephrine
go.drugbank.com/drugs/DB00388ApprovedInvestigational[A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s.[A187376] Phenylephrine was granted FDA approval in 1939.[L9413] … Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction.
Synonyms: l-(3-Hydroxyphenyl)-N-methylethanolamineMixtures: DOLEX® CONTRA LOS SINTOMAS DE LA GRIPA TABLETAS., Cough-en RX LinctusCetrimonium
go.drugbank.com/drugs/DB01718ApprovedInvestigationalCetrimonium is a quaternary ammonium cation whose salts are used as antiseptics.
Synonyms: N,N,N-Trimethyl-1-hexadecanaminiumCategories: Compounds used in a research, industrial, or household settingBivalirudin
go.drugbank.com/drugs/DB00006ApprovedInvestigationalOnce bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. … Because it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial thromboplastin time, international normalized ratio and blood pressure.
Products: Bivalirudin in 0.9% Sodium Chloride, BIVACARD 250 MG IV ENJEKSIYON VE INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADETFlunisolide
go.drugbank.com/drugs/DB00180ApprovedFlunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoi...
Products: FLUNISOLIDE EG, FLUNISOLIDE MYLAN GENERICSZolmitriptan
go.drugbank.com/drugs/DB00315ApprovedInvestigationalIt is currently available in both tablet and nasal spray forms.[L12978] … [A193791] Triptans can be administered alone or in combination with an NSAID like [naproxen], and represent the current "gold standard" for acute migraine treatment.
Products: CAMIGRAN TABLETAS, ZOLMITRIPTAN MYLAN GENERICSIpriflavone
go.drugbank.com/drugs/DB13618InvestigationalProducts: IPRIFLAVONA TABLETAS 200 MG, OSTEOFLAVONA 200 MG TABLETASFurazolidone
go.drugbank.com/drugs/DB00614InvestigationalVet approved(From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
Synonyms: N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone, 5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimineProducts: FELIDIAR TABLETAS, FUROXONA TABLETAS 100MGMesterolone
go.drugbank.com/drugs/DB13587InvestigationalMesterolone demonstrated to have minimal effect on sperm counts and levels of FSH or LH [A27177, A27178]. … It is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen.
Products: PROVIRON TABLETAS, PROVIRON ® TABLETASChloramphenicol
go.drugbank.com/drugs/DB00446ApprovedInvestigationalVet approvedWithdrawn(From Martindale, The Extra Pharmacopoeia, 29th ed, p106) The FDA has withdrawn all oral drug products containing chloramphenicol, due to the high risk of fatal aplastic anemia associated with this … An antibiotic first isolated from cultures of _Streptomyces venezuelae_ in 1947 but now produced synthetically.
Synonyms: D-(−)-2,2-dichloro-N-(β-hydroxy-α-(hydroxymethyl)-p-nitrophenylethyl)acetamide, D-(−)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediolProducts: PALMITATO DE CHLOROMYCETINDoxepin
go.drugbank.com/drugs/DB01142ApprovedInvestigational[T559] It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to [cidoxepin]. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. … [L5977] Doxepin was developed by Pfizer and FDA approved in 1969 as an antidepressant.[L5971] However, in 2010 it was approved for the treatment of insomnia.
Products: Jamp Doxepin Tablets