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Cisapride
go.drugbank.com/drugs/DB00604ApprovedWithdrawnThe FDA issued a warning letter regarding this risk to health care professionals and patients. … In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: DISPEPRID 5 MG TABLET, 30 ADET, GUARPOSID - 5Ferric hydroxide
go.drugbank.com/drugs/DB13423InvestigationalProducts: FERIFER-40 ORAL COZELTI 40 MG/5 ML KAŞIK, 28 ADET, FERIFER 100 MG/5 ML ORAL COZELTI ICEREN KAŞIK, 20 ADETBumetanide
go.drugbank.com/drugs/DB00887ApprovedInvestigationalBumetanide is a sulfamyl diuretic.
Mixtures: BURINEX TABLET 1 mg, BURINEX TABLET 1 mgSynonyms: 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid, 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acidArsenic trioxide
go.drugbank.com/drugs/DB01169ApprovedInvestigationalIn general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous adverse effects. … The enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsProducts: LEUSENOX 2 MG/ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 10 ADET, TRISENOX 1 MG/1 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 10 ADETValganciclovir
go.drugbank.com/drugs/DB01610ApprovedInvestigationalValganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. … As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Categories: Heterocyclic Compounds, 2-RingProducts: RUNAVIR®450 MG, VALGOVIR® 450 MGCalcium
go.drugbank.com/drugs/DB01373ApprovedInvestigationalNutraceuticalCirculating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. … Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways.
Mixtures: OSMEGA 600 MG/400 IU/25 MG EFERVESAN TABLET, 30 ADET, OSMEGA 600 MG/400 IU/25 MG EFERVESAN TABLET, 60 ADETCategories: ascorbic acid (vit C) and calciumNatalizumab
go.drugbank.com/drugs/DB00108ApprovedInvestigational[A261331] On August 24, 2023, the first biosimilar to natalizumab, natalizumab-sztn, was approved by the FDA.[L48041] Natalizumab was approved by the European Commission on September 22, 2023. … Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin.
Synonyms: IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL AN100226 LIGHT CHAIN, DIMER, IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL AN100226 LIGHT CHAIN, DIMERProducts: Tysabri 150 mg SC Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör (2 adet), TYSABRI 300 MG I.V. INFUZYON ICIN KONSANTRE COZELTI ICEREN FLAKON, 1 ADETLubiprostone
go.drugbank.com/drugs/DB01046ApprovedInvestigationalA prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastrointestinal epithelial cells. … Lubiprostone is a medication used in the management of idiopathic chronic constipation.
Categories: Prostaglandins EProducts: MOVIPROST 24 MCG, MOVIPROST ® 8 MCGBuserelin
go.drugbank.com/drugs/DB06719ApprovedInvestigationalIt is used in prostate cancer treatment. … Buserelin is a synthetic peptide analog of the luteinizing hormone-releasing hormone (LHRH) agonist, which stimulates the pituitary gland's gonadotrophin-releasing hormone receptor (GnRHR).
Products: Suprefact Depot 2 Months, SUPREFACT INJECTABLE 1 mg/mlVinblastine
go.drugbank.com/drugs/DB00570ApprovedInvestigationalAntitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: VINBLASTINE RICHTER 5 MG FLAKON, VINBLASTINA10 MG X 1 FCO.