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Influenza A virus A/California/7/2009 X-181 (H1N1) antigen (UV, formaldehyde inactivated)
go.drugbank.com/drugs/DB14612ApprovedWithdrawnInactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
Synonyms: Influenza A virus A/California/7/2009 X-181 (H1N1) antigen (UV, formaldehyde inactivated)Trastuzumab
go.drugbank.com/drugs/DB00072ApprovedInvestigationalIt is suggested that the overexpression or gene amplification of HER2 has been found in about 20–30% of breast cancers and elevated activation of HER2 triggers multiple downstream pathways leading to abnormal … Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody [A40276] that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular
Mixtures: PHESGO® 1200 MG/600 MG, PHESGO® 1200 MG/600 MGProducts: HERCEPTIN (SOLUTION FOR INJECTION 600 MG/5 ML), HERCEPTİN 600 MG/5 ML S.C. ENJEKSİYONLUK ÇÖZELTİ, 1 ADETCidofovir
go.drugbank.com/drugs/DB00369ApprovedInvestigationalCidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. … [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since been discontinued.[L6223]
Products: CIDOFOVIR INJECTION 375 MG/5 ML (75 MG/ML), CIDOFOVIR INJECTION 375 MG/5MLDabrafenib
go.drugbank.com/drugs/DB08912ApprovedInvestigational[L41955] In May 2018, Tafinlar (dabrafenib), in combination with Mekinist ([DB08911]), was approved to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene.[L41955] … It was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation.[L41955] It was also used for metastatic non-small cell lung cancer with the same mutation.
Products: TAFINLAR 50 MG KAPSUL, 20 ADET, TAFINLAR (CAPSULES 50 MG)Gadobenic acid
go.drugbank.com/drugs/DB00743ApprovedInvestigational[A1139] Gadobenate dimeglumine was approved by the FDA in November 2004 under the brand name MultiHance.[A263166] … [A263086] It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity.
Mixtures: MULTIHANCE INJECTION 10 ML, MULTIHANCE INJECTION 10 MLCategories: Compounds used in a research, industrial, or household settingSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigational[A242372] In November 2000, the drug was recognized by the European Agency as an alternative to calcineurin antagonists for maintenance therapy with corticosteroids. … Sirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria _Streptomyces hygroscopicus_, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island
Products: LIKMUN-E, RAPAMUNE 1 MG 100 FILM DRAJEClodronic acid
go.drugbank.com/drugs/DB00720ApprovedInvestigationalVet approved[A203111] Clodronic acid is not FDA approved, but is approved in Canada.[L13910] … [A1923] clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]
Products: BONEFOS 800 MG TABLET, 60 ADET, ACIDO CLODRONICO EGAlteplase
go.drugbank.com/drugs/DB00009ApprovedInvestigational[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. … [A252330,L43125] Alteplase is a purified glycoprotein of 527 amino acids expressed in Chinese hamster ovary (CHO) cells.
Products: ACTILYSE 20 MG FLAKON, 1 ADET, ACTILYSE 10 MG FLAKON, 1 ADETCilostazol
go.drugbank.com/drugs/DB01166ApprovedInvestigationalCilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia
Categories: Compounds used in a research, industrial, or household settingProducts: CILOSTAZOLO EG, ANGIOVAN®100 MGPentoxyverine
go.drugbank.com/drugs/DB11186ApprovedWithdrawnPentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate. … It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists [A32160].
Mixtures: GAYABEN 150 ML SURUP, Exall DProducts: PENTOXYVERIN AL 1.35 MG/ML, Mucomat Hustenstiller 2,13 mg/ml Lösung zum Einnehmen