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Migalastat
go.drugbank.com/drugs/DB05018ApprovedInvestigationalwhere the agency determines that the drug if approved, would provide a significant improvement in treating, diagnosing or preventing a serious condition over available therapies. … [L4274] Migalastat (approved and sold under Amicus Therapeutics' brand name Galafold) is subsequently an oral pharmacological chaperone of alpha-Gal A for the treatment of Fabry disease in adults who
Products: GALAFOLD 123 MG SERT KAPSÜL, 14 ADETLindane
go.drugbank.com/drugs/DB00431ApprovedWithdrawntreatment of pediculosis capitis (head lice), pediculosis pubis (pubic lice), or scabies in patients greater than two years of age who cannot tolerate or have failed first-line treatment. … Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment.
Categories: Compounds used in a research, industrial, or household settingCalcipotriol
go.drugbank.com/drugs/DB02300ApprovedInvestigationalCalcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Mixtures: Daivobet 50 Mikrogramm/g + 0,5 mg/g Gel, Calcidermetha 50 Mikrogramm/g + 0,5 mg/g GelProducts: PSORCUTAN KREM, 30 G, DAIVONEX OINTMENT 50 mcg/gCaptopril
go.drugbank.com/drugs/DB01197ApprovedInvestigationalATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension. … Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).
Mixtures: CAPOZIDE 50/25 MG TABLETASCategories: Agents Acting on the Renin-Angiotensin SystemVoxilaprevir
go.drugbank.com/drugs/DB12026ApprovedInvestigationalVosevi is approved for the treatment of adult patients with chronic HCV infection with genotype 1, 2, 3, 4, 5, or 6 infection [FDA Label]. … Notably, Vosevi is approved for use in patients with genotypes 1-6 who have been previously treated with an NS5A inhibitor, or patients with genotypes 1a or 3 infection and have previously been treated
Mixtures: VOSEVİ 400 MG/ 100 MG/ 100 MG FİLM KAPLI TABLET, 28 ADETCategories: Antivirals for treatment of HCV infectionsLunacalcipol
go.drugbank.com/drugs/DB05024InvestigationalCTA018 is a member of a new class of vitamin D analogues with a dual mechanism of action, called Vitamin D Signal Amplifiers. … This proprietary new drug is both a potent inhibitor of CYP24 (the enzyme responsible for the breakdown of vitamin D) and a potent activator of vitamin D signaling pathways.
Sacubitril
go.drugbank.com/drugs/DB09292ApprovedInvestigationalIt was approved by the FDA after being given the status of priority review for on July 7, 2015. … Inhibition of neprilysin therefore leads to reduced breakdown and increased concentration of endogenous natriuretic peptides in addition to increased levels of vasoconstricting hormones such as angiotensin
Mixtures: ENTRESTO 200 MG, ENTRESTO 50 MGPrussian blue
go.drugbank.com/drugs/DB06783ApprovedIt is orally administered for clinical purposes to be used as an antidote for certain kinds of heavy metal poisoning, such as thallium and radioactive isotopes of caesium. … Prussian blue is described as a deep blue pigment that is produced when the oxidation of ferrous ferrocyanide salts occurs.
Categories: Compounds used in a research, industrial, or household settingEnoxaparin
go.drugbank.com/drugs/DB01225ApprovedInvestigational[L31393] Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients when compared to unfractionated [heparin], without increasing the risk of serious bleeding. … Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders.
Mixtures: ENOXAPARINA SODICA 40 MG JERINGAS PRELLENADASProducts: KLEXANE 10000 IE 100MG O S, KLEXANE 4000 IE 40MG O SI.Molnupiravir
go.drugbank.com/drugs/DB15661Investigational[A193026] The active drug incorporates into the genome of RNA viruses, leading to an accumulation of mutations known as viral error catastrophe. … Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of [N4-hydroxycytidine].