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Pegzilarginase
go.drugbank.com/drugs/DB14780ApprovedFDA in February 2026 for the treatment of hyperargininemia in adult and pediatric patients aged 2 years and older with ARG1-D, to be used in conjunction with dietary protein restriction.
Mangafodipir
go.drugbank.com/drugs/DB06796ApprovedInvestigationalWithdrawnTeslascan has been removed from the Drug Product List by FDA in 2003, and withdrawn from the European market in 2012.
Fluoroestradiol F-18
go.drugbank.com/drugs/DB15690ApprovedInvestigational[A203912] Fluoroestradiol F-18 was first granted FDA approval in May 2020, and will be developed by PETNET Solutions, Inc. and Zionexa USA under the brand name Cerianna.
Fentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approved[L6751] Fentanyl was FDA approved in 1968.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613]
Trazodone
go.drugbank.com/drugs/DB00656ApprovedInvestigational[T646] It was initially granted FDA approval in 1981.[L3484]
Estriol
go.drugbank.com/drugs/DB04573ApprovedInvestigationalVet approvedThough estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy, it is not approved for use by the FDA or Health Canada.
Digoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigational[A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954.
Methocarbamol
go.drugbank.com/drugs/DB00423ApprovedInvestigationalVet approved[L6295] Methocarbamol was FDA approved on 16 July 1957.[L6265]
Anthrax immune globulin human
go.drugbank.com/drugs/DB09057ApprovedInvestigationalAvailable as the product Anthrasil (FDA), the result is a solution for slow IV infusion containing polyclonal antibodies that bind the protective antigen (PA) component of Bacillus anthracis lethal and
Peramivir
go.drugbank.com/drugs/DB06614ApprovedInvestigationalThe injectable intravenous formulation of peramivir was approved by the FDA in September 2017 for the treatment of acute uncomplicated influenza to pediatric patients 2 years and older who have been symptomatic