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Rifampin
go.drugbank.com/drugs/DB01045ApprovedInvestigational[A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).[A263768] … Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and clinically used in 1968.
Mixtures: RIFAMPICINA 300MG+ISONIAZIDA 150MG, Rifoldin 300 mg mit INH DrageesCategories: dapsone and rifampicin, rifampicin and isoniazidBrinzolamide
go.drugbank.com/drugs/DB01194Approved[A2051] Brinzolamide was approved by the FDA in 1998 as a standalone product and in 2013 as a combination product with brimonidine tartrate. … [A2049,A2051] Although systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of success, systemic administration results in an increase in incidences of adverse
Mixtures: AZARGA 10MG/ML+5MG/ML, AZARGA 10MG/ML + 5MG/MLCategories: Antiglaucoma Preparations and Miotics, Genito Urinary System and Sex HormonesRitonavir
go.drugbank.com/drugs/DB00503ApprovedInvestigationalAlthough it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors … Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV.
Mixtures: Kaletra Tablet 100mg/25mg, Kaletra 100mg/25mg Film-Coated TabletCategories: Antivirals used in combination for the treatment of HIV infections, lopinavir and ritonavirCanagliflozin
go.drugbank.com/drugs/DB08907ApprovedInvestigationalIt was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 for a second indication of reducing the risk of cardiovascular events in patients diagnosed with type … Canagliflozin, also known as _Invokana_, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise
Mixtures: Vokanamet (Canagliflozin 150mg/ Metformin 500mg) Film-Coated Tablet, Vokanamet (Canagliflozin 150mg/ Metformin 1000mg) Film-Coated TabletCategories: Drugs Used in Diabetes, Alimentary Tract and MetabolismMannitol
go.drugbank.com/drugs/DB00742ApprovedInvestigationalMannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. … On October 30, 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients and is currently marketed for
Mixtures: INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion), TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL Red Cell PreservativeCategories: Compounds used in a research, industrial, or household setting, Diet, Food, and NutritionDexpanthenol
go.drugbank.com/drugs/DB09357ApprovedInvestigationalDexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. … Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism
Mixtures: BEPANTHEN PLUS 50 MG/5MG KREM, 30 G, B Complex W C and B12 InjCategories: Vitamin D and Analogues, Alimentary Tract and MetabolismHydrocodone
go.drugbank.com/drugs/DB00956ApprovedIllicitInvestigationalHydrocodone's more potent metabolite, [hydromorphone] has also found wide use as an analgesic and is frequently used in cases of severe pain. … Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by [dextromethorphan] in current cough and cold formulations.
Mixtures: FEMTAX® 5MG/325MG, Hydrocodone Bitartrate and AcetaminophenCategories: Cough and Cold Preparations, hydrocodone and ibuprofenCisatracurium
go.drugbank.com/drugs/DB00565ApprovedInvestigational[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. … [A243416,A253592] Cisatracurium is an R-cis-R-cis isomer of [atracurium] and has approximately 3 times its neuromuscular blocking potency.
Synonyms: Cisatracurium ionProducts: Nimbex 10mg/ml, KABICURIUM® 10MG/5MLBelimumab
go.drugbank.com/drugs/DB08879ApprovedInvestigationalIt is produced by recombinant DNA technology in a murine cell (NS0) expression system. … [A251495, L42705] By binding to BLyS and blocking its interaction with B cell receptors, belimumab inhibits the survival of B cells.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: Benlysta Powder for Solution for Infusion 120mg, BENLYSTIA IVCabazitaxel
go.drugbank.com/drugs/DB06772ApprovedInvestigational[A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17, 2019.[L47376] … [A7056] Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and [docetaxel].
Categories: Antineoplastic and Immunomodulating AgentsProducts: JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION, Concentrate and Solvent for Solution for Infusion 60mg/1.5ml