Dexpanthenol is an alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN). Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium.
- Mechanism
- Curator reviewed · 2 references
Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium.
Dermatological effects of the topical use of dexpanthenol include increased fibroblast proliferation and accelerated re-epithelialization in wound healing. Furthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties.
- Primary indication
- Injection: Prophylactic use immediately after major abdominal surgery to minimize the possibility of paralytic ileus.Curator reviewed · 44 structured indications
- Formula / weight
- C9H19NO4 · 205.2515 g/mol (avg)
- First approval
- Canada, 2001 · United States, 2001
- Also known as
- Bepanthen · Bepanthene · Bepantol · D-panthenol · D-panthenol 50
- Code names
- 201-327-3 · BAY 81-2996 · NSC-302962
- Brand names
Resolves to
SNPLKNRPJHDVJA-ZETCQYMHSA-NSMILESCC(C)(CO)[C@@H](O)C(=O)NCCCOWhat you can answer from here — as of September 29, 2026
Which other approved drugs treat the same conditions as Dexpanthenol, and which companies have late-stage candidates in those indications?
Create a free account or log in to explore the full data card.
Create Account