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Interferon gamma-1b
go.drugbank.com/drugs/DB00033ApprovedInvestigationalHuman Interferon gamma-1b (140 residues), produced from E. coli. … The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray et. al. and not specifically interferon gamma 1b.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: IMUKIN 100 Mikrogramm/0,5 ml InjektionslösungFibrinogen human
go.drugbank.com/drugs/DB09222ApprovedInvestigationalIt is a soluble plasma glycoprotein with a molecular weight of about 340 kDa and is a physiological substrate for three enzymes: plasmin, factor XIIIa, and thrombin. … Fibrinogen concentrate (human) is a hematological agent. It works by replacing a specific protein in the blood, fibrinogen (factor I), that helps with blood clotting.
Mixtures: EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml, TACHOSİL 5,5 MG/CM2 İNSAN FİBRİNOJENİ VE 2.0 IU/CM2 İNSAN TROMBİNİ İLAÇLI SÜNGERProducts: VERASEAL SOLUTIONS FOR SEALANT, 80 mg/ml, 500 IU/ml, Haemocomplettan P 1g/2g Pulver zur Herstellung einer Injektions-/InfusionslösungEfmarodocokin alfa
go.drugbank.com/drugs/DB16398InvestigationalEfmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
Synonyms: HUMAN INTERLEUKIN 22 (1-146), FUSED TO HUMAN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 4 (CH1(97-98), H(S10>P(158)), CH2(N67>G(227)))-(147-377), DIMER (156-156':159-159')-BISDISULFIDE, PRODUCED IN CHO CELLS,Erythropoietin
go.drugbank.com/drugs/DB00016ApprovedInvestigationalvarious clinical conditions, such as chronic renal failure, antiviral drug therapy, chemotherapy, or a high risk for perioperative blood loss from surgical procedures [FDA Label]. … The biosimilar is approved by the FDA and EMA as a safe, effective and affordable biological product and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504].
Products: EPORON 10000 IU/1,0 ML KULLANIMA HAZIR 10 ENJEKTOR, Binocrit 10 000 IU/1 ml solution for injection in a pre-filled syringeExametazime
go.drugbank.com/drugs/DB11179ApprovedIt acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex. … Exametazime is a diagnostic radiopharmaceutical agent commonly used for the preparation of Tc99m Exametazime injection.
Products: CERETEC FOR INJECTION 0.5 mg/vial, CERETEC ESTABILIZADO KIT DE 500 MICROGRAMOS PARA PREPARACIÓN RADIOFARMACÉUTICARemifentanil
go.drugbank.com/drugs/DB00899ApprovedInvestigationalRemifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia. … Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic.
Products: REMIFENTANILO 2 MG POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE, REMIFENTANILO 2MG POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE O INFUSION INTRAVENOSASelumetinib
go.drugbank.com/drugs/DB11689ApprovedInvestigationalNF-1 is considered rare, with an estimated incidence of 1/3000 individuals. … [A193533] Following its initial FDA approval on April 10, 2020,[L49991] and Health Canada approval on August 23, 2022,[L49986] the regulatory landscape has evolved.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: Koselugo Hard Capsules 10 mg, Koselugo Hard Capsules 25 mgQuinagolide
go.drugbank.com/drugs/DB09097ApprovedWithdrawnQuinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated levels of prolactin or hyperprolactinaemia. … It is typically present in the hydrochloride salt form and is marketed as oral tablets under the brand name Norprolac contained as a racemate.
Synonyms: (+-)-N,N-Diethyl-N'-((3R*,4aR*,10aS*)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin-3-yl)sulfamideCategories: Dopamine D2 Receptor AgonistsChlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalChlorthalidone has been shown to have a number of pleiotropic effects that differentiate it from other diuretics such as [DB00999]. … Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment.
Mixtures: TENORETIC 100 MG/25 MG FILM TABLET, 28 ADET, BRASARTAN® CTDN 160/25 MGProducts: CLORTAX 50 MG TABLETAS, Uldiulan 50 mg TablettenDifluocortolone
go.drugbank.com/drugs/DB09095ApprovedWithdrawnIt was submitted to the FDA in July 1984 by the pharmaceutical company Schering AG.[L1082] … Difluocortolone is a potent topical corticosteroid. It is commonly used in dermatology for the reduction of inflammation and itching.
Mixtures: TRODERM 10 MG/G+1 MG/G KREM ,15 G, TİNAGEN 1 MG+10 MG/1 G DERİ KREMİ, 15 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers