Search

Displaying results 111 - 120 of 4188 in total
  1. Drug

    Alendronic acid

    go.drugbank.com/drugs/DB00630
    ApprovedInvestigational

    Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label] . It functions by preventing resorption of bone[FDA Label] .

    Products: Gen-alendronate
  2. Drug

    AAV-AIPL

    go.drugbank.com/drugs/DB17857
    Experimental

    AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human _AIPL1_ gene. … Developed by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due to defects in _AIPL1_ gene.

    Synonyms: adenovirus associated viral vector serotype 8 containing the human AIPL1 gene
  3. Drug

    Furosemide

    go.drugbank.com/drugs/DB00695
    ApprovedInvestigationalVet approved

    Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. … Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients.

    Products: Steril-Gene Furosemide Injection BP 20mg/2ml Solution for Injection or infusion
  4. Drug

    Adenovirus/PNP

    go.drugbank.com/drugs/DB17175
    Investigational

    Synonyms: adenoviral vector expressing the E.coli purine nucleoside phosphorylase gene
  5. Drug

    CypCaps

    go.drugbank.com/drugs/DB17435
    Experimental

    Synonyms: Cytochrome P450 isoform 2B1 gene transfected human embryonic kidney 293 cells encapsulated in polymeric cellulose sulphate
  6. Drug

    Benzethonium

    go.drugbank.com/drugs/DB11125
    Approved

    There is evidence that benzethonium acts as a spermatocide but may cause vaginal irritation [A32304].

    Mixtures: Green Guard Burn First Aid, Green Guard Antiseptic First AidProducts: LYSOL Healthy Touch Cleansing Green Tea and Ginger
  7. Drug

    Tofersen

    go.drugbank.com/drugs/DB14782
    ApprovedInvestigational

    Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS).

    Synonyms: Antisense Oligonucleotide Inhibitor Of The Expression Of Superoxide Dismutase 1 Gene
  8. Drug

    Volrubigene ralaparvovec

    go.drugbank.com/drugs/DB16785
    Investigational

    Volrubigene ralaparvovec is under investigation in clinical trial NCT03223194 (Gene Transfer Clinical Study in Crigler-najjar Syndrome).

    Synonyms: Non-replicating recombinant adeno-associated viral vector, serotype 8, expressing the 1A1 isoform of the bilirubin-uridine diphosphate glucuronosyltransferase gene
  9. Drug

    TN-401

    go.drugbank.com/drugs/DB18140
    Investigational

    TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.

    Synonyms: A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene
  10. Drug

    OTL-203

    go.drugbank.com/drugs/DB18643
    Investigational

    OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.

    Synonyms: Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene