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Glycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers. … [A233565] Glycopyrronium was originally granted FDA approval on 11 August 1961.[L33090]
Mixtures: ENERZAIR BREEZHALER INHALATION POWDER, HARD CAPSULE 150 MCG /50 MCG /160 MCG, ULTIBRO BREEZHALER INHALATION POWDER HARD CAPSULE 110/50 MCGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesTapentadol
go.drugbank.com/drugs/DB06204ApprovedInvestigationalIt is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. … The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: Nucynta ER Tablets 100 mg, PALEXIS® RETARD 100 MGOxaliplatin
go.drugbank.com/drugs/DB00526ApprovedInvestigational[A797] Although oxaliplatin has been investigated as a monotherapy, it is typically administered in combination with fluorouracil and leucovorin, known as the FOLFOX regimen, for the treatment of colorectal … Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin.
Products: OXALIPLATINO 50 MG / 10 ML, OXALITIN INJECTION 50 MG/10 MLThalidomide
go.drugbank.com/drugs/DB01041ApprovedInvestigationalWithdrawnA piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects. … It has been reintroduced and used for a number of inflammatory disorders and cancers.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersInternational brands: Pro-ban MRituximab
go.drugbank.com/drugs/DB00073ApprovedInvestigationalIt was originally approved by the U.S. … FDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however, has now been approved for a variety of conditions [FDA label].
Categories: CD20 (Clusters of Differentiation 20) inhibitorsProducts: MABTHERA ® CONCENTRADO DE SOLUCIÓN PARA INFUSIÓN 500 MG / 50 ML, NOVEX 500 MG/50 ML I.V. İNFÜZYONLUK ÇÖZELTİ İÇİN KONSANTRE, 1 FLAKONTheophylline
go.drugbank.com/drugs/DB00277ApprovedInvestigationalMechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. … Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD.
International brands: Theodur GMixtures: THEOLONG 1200/400 MG EFERVESAN TABLET, 10 ADET, THEOLONG 600/200 MG EFERVESAN TABLET, 10 ADETErsodetug
go.drugbank.com/drugs/DB18182InvestigationalSynonyms: gamma2 heavy chain Homo sapiens (1-444) [VH(Homo sapiens IGHV3-20*01 (98.0%) -(IGHD)-IGHJ6*01 (93.8%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG2*02 (100%), G2m23 CH2 M45.1 (CH1Mesalazine
go.drugbank.com/drugs/DB00244ApprovedInvestigationalAlthough demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent
Synonyms: m-Aminosalicylic acid, 5-ASAProducts: SALOFALK GRANÜ-STİX 1000 MG GRANÜL İÇEREN SAŞE, 50 ADET, SALOFALK 500 MG ENTERİK TABLET, 50 ADETTrazodone
go.drugbank.com/drugs/DB00656ApprovedInvestigational[T646] It was initially granted FDA approval in 1981.[L3484] … [A181180] It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine
Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsProducts: AZONA 100 MG KAPSÜL, 30 ADET, DESYREL XL 150 MG UZATILMIŞ SALIMLI FİLM TABLET , 10 TABLETFentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approved[L6751] Fentanyl was FDA approved in 1968.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: FENTANYL 0,05 MG/ML 10 ML SOLÜSYON İÇEREN IV AMPUL, 50 ADET, FENTANEST 500 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ (10 ADET)