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Lindane
go.drugbank.com/drugs/DB00431ApprovedWithdrawnIn Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity, and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical
Lenacapavir
go.drugbank.com/drugs/DB15673ApprovedInvestigational[L42995] On December 22, 2022, it was also approved by the FDA.[L44473]
Lutetium Lu-177 vipivotide tetraxetan
go.drugbank.com/drugs/DB16778ApprovedInvestigational[L41280] Lutetium Lu-177 vipivotide tetraxetan was first approved by the FDA on March 23, 2022 as a treatment for prostate-specific membrane antigen–positive metastatic castration-resistant prostate
Oxybutynin
go.drugbank.com/drugs/DB01062ApprovedInvestigationalOxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for the relief of overactive bladder symptoms that has been optimized for high levels of safety and efficacy since initial FDA
Mavorixafor
go.drugbank.com/drugs/DB05501ApprovedInvestigational[L50642] It was first approved by the FDA on April 30, 2024, for the treatment of warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome, a genetic immunodeficiency disorder characterized
Parathyroid hormone
go.drugbank.com/drugs/DB05829ApprovedInvestigationalFood and Drug Administration (FDA).
Tapinarof
go.drugbank.com/drugs/DB06083ApprovedInvestigational[A248790] Tapinarof received initial approval from the FDA in 2022.[L41845]
Cabazitaxel
go.drugbank.com/drugs/DB06772ApprovedInvestigationalIt was first approved by the FDA on June 17, 2010.[A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17, 2019.[L47376]
Pibrentasvir
go.drugbank.com/drugs/DB13878ApprovedInvestigationalthe emergence of amino acid substitutions at known NS5A inhibitor resistance-associated positions in HCV genotype 1a, 2a or 3a replicons led to reduced susceptibility and resistance to pibrentasvir [FDA … This fixed-dose combination therapy was FDA-approved in August 2017 to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis, including
Pravastatin
go.drugbank.com/drugs/DB00175ApprovedInvestigational.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved in 1991.
Products: Nra-pravastatin