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Displaying results 1211 - 1220 of 10000 in total

Drug
Merimepodib
go.drugbank.com/drugs/DB04862
Investigational
Merimepodib (VX-497) is a novel noncompetitive inhibitor of IMPDH.
Drug
Huperzine A
go.drugbank.com/drugs/DB04864
ApprovedInvestigationalWithdrawn
Huperzine A, is a naturally occurring sesquiterpene alkaloid found in the extracts of the firmoss _Huperzia serrata_. … It is currently being investigated as a possible treatment for diseases characterized by neurodegeneration – particularly Alzheimer’s disease.
Categories: Compounds used in a research, industrial, or household settingSynonyms: L-huperzine A, Huperzine A
Drug
Halofuginone
go.drugbank.com/drugs/DB04866
InvestigationalVet approved
Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (+/-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone
Drug
Oleoyl-estrone
go.drugbank.com/drugs/DB04870
Investigational
Oleoyl-estrone (OE) is a fatty acid ester of estrone. This hormone occurs naturally and is found circulating in various animal species and humans.
Synonyms: Estrone 3-oleate
Drug
Piboserod
go.drugbank.com/drugs/DB04873
Investigational
Piboserod (SB 207266) is a selective 5-HT(4) receptor antagonist.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
Drug
Enoximone
go.drugbank.com/drugs/DB04880
ApprovedInvestigationalWithdrawn
Enoximone is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption.
Categories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 3 Inhibitors
Drug
Elacridar
go.drugbank.com/drugs/DB04881
Investigational
In many cases, the appearance of multidrug resistance in cancer is due to a change in expression of protein inhibitors. As of August 2007 elacridar was not listed on GSK's product pipeline.
Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-Ring
Drug
Edotecarin
go.drugbank.com/drugs/DB04882
Investigational
Edotecarin is a novel, non-camptothecin, DNA topoisomerase I inhibitor. It is member of the class of compounds called indolocarbazoles.
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-Ring
Drug
Darusentan
go.drugbank.com/drugs/DB04883
Investigational
Darusentan is a selective endothelin ETA receptor antagonist. It is being evaluated as a treatment for congestive heart failure and hypertension.
Categories: Heterocyclic Compounds, 1-Ring
Drug
Dapoxetine
go.drugbank.com/drugs/DB04884
Investigational
In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo. … Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.
Mixtures: TADA PLUS 30/20 MG FILM KAPLI TABLET ,4 ADET, TADA PLUS 30/20 MG FILM KAPLI TABLET ,8 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors