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Displaying results 1241 - 1250 of 10000 in total
  1. Drug

    Rifapentine

    go.drugbank.com/drugs/DB01201
    ApprovedInvestigational

    Rifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells.

    Categories: Heterocyclic Compounds with 4 or More Rings, Cytochrome P-450 SubstratesSynonyms: 3-(((4-Cyclopentyl-1-piperazinyl)imino)methyl)rifamycin
  2. Drug

    Chlorthalidone

    go.drugbank.com/drugs/DB00310
    ApprovedInvestigational

    These pathways may play a role in chlorthalidone's cardiovascular risk reduction effects.[A176330] … [A173884, A173887] Further studies have indicated that low-dose thiazides are as good as, and in some secondary endpoints, better than β-blockers, ACE inhibitors, Calcium Channel Blockers or ARBs.

    Mixtures: BRASARTAN® CTDN 160/25 MG, BRASARTAN® CTDN 80/25 MGCategories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Medrysone

    go.drugbank.com/drugs/DB00253
    Approved

    Medrysone is a corticosteroid used in ophthalmology.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: 11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione
  4. Drug

    2,4-deoxy-4-guanidino-5-N-acetyl-neuraminic acid

    go.drugbank.com/drugs/DB03420
    Experimental

    Synonyms: (2R,4S,5R,6R)-5-Acetamido-4-(diaminomethylideneamino)-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid, 2,4-deoxy-4-guanidino-5-N-acetyl-neuraminic acid
  5. Drug

    Morpholinylmercaptobenzothiazole

    go.drugbank.com/drugs/DB14202
    Approved

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 2-(4-Morpholino)thiobenzothiazole, 4-(1,3-benzothiazol-2-ylsulfanyl)morpholine
  6. Drug

    Nomifensine

    go.drugbank.com/drugs/DB04821
    ApprovedWithdrawn

    FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal Register of June 17, 1986 (51 FR 21981)).

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine, 8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline
  7. Drug

    Alrizomadlin

    go.drugbank.com/drugs/DB17549
    Investigational

    Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]

    Synonyms: 4-((3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo [2.2.2]octane-1-carboxylic acid, (3'r,4's,5'r)-4-((6-chloro-2-oxo-1,2-dihydro-spiro(indole-3,3'-pyrrolidin)e-4'-(3-chloro-2-fluoro -phenyl)-1'-ethyl-spiro(cyclohexane-1,2'-pyrrolidine)-5'-carbonyl)-amino)-bicyclo(2.2.2)octane-1-carboxylic
  8. Drug

    Acitretin

    go.drugbank.com/drugs/DB00459
    ApprovedInvestigational

    An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.

    Categories: Skin and Mucous Membrane AgentsSynonyms: (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid, all-trans-3,7-Dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid
  9. Drug

    2-Amino-4-(4-Amino-Cyclohexa-2,5-Dienyl)-Butyric Acid

    go.drugbank.com/drugs/DB02725
    Experimental

    Synonyms: 2-Amino-4-(4-Amino-Cyclohexa-2,5-Dienyl)-Butyric Acid
  10. Drug

    (2R,3R)-2,3-Dihydroxy-4-oxo-4-(propylamino)butanoic acid

    go.drugbank.com/drugs/DB03390
    Experimental

    Synonyms: (2R,3R)-2,3-Dihydroxy-4-oxo-4-(propylamino)butanoic acid, N-Propyl-L-tartramate