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Levoketoconazole
go.drugbank.com/drugs/DB05667ApprovedStill, toxicity has limited its use, notably hepatic toxicity and a tendency to prolong the QT interval.[A244083] Levoketoconazole is one of two enantiomers present in racemic [ketoconazole]. … It possesses most of the inhibitory effect towards steroidogenic enzymes, making it an attractive candidate for CS treatment with a potentially lower toxicity profile than its racemate.
Categories: MATE 1 Inhibitors, P-glycoprotein inhibitorsDesonide
go.drugbank.com/drugs/DB01260ApprovedInvestigationalA nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Mixtures: SPORUM-D, APOLAR NCategories: Corticosteroids, Moderately Potent (Group II), Cytochrome P-450 SubstratesMoxetumomab pasudotox
go.drugbank.com/drugs/DB12688ApprovedInvestigationalCD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia, hairy cell leukemia, acute lymphocytic leukemiathe and Burkitt's lymphoma. … This antibody was used to generate a recombinant immunotoxin in which a stabilized Fv segment by a disulfide bond is fused to the _Pseudomonas_ exotoxin A (PE38) which does not have the cell-binding portion
Dolutegravir
go.drugbank.com/drugs/DB08930ApprovedInvestigationalDolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). … [L1035] On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named
Mixtures: TRIUMEQ® 50 MG / 600 MG / 300 MGCategories: MATE 1 Inhibitors, P-glycoprotein substratesForeskin fibroblast (neonatal)
go.drugbank.com/drugs/DB10770ApprovedAlso known as Dermagraft, this device is a cryopreserved human fibroblast-derived dermal substitute. … Dermagraft has been combined with [DB10772] to create a drug beneficial to patients with open burn wounds [L2427].
Rocaglamide
go.drugbank.com/drugs/DB15495ExperimentalRocaglamide, also referred to as rocaglamide-A, is the eponymous member of a class of anti-cancer phytochemicals known as rocaglamides. … [A186760] Rocaglamide and a number of its derivatives (e.g.
Categories: Heterocyclic Compounds, 2-RingInfluenza B virus B/Austria/1359417/2021 live (attenuated) antigen
go.drugbank.com/drugs/DB16902ApprovedUpon re-exposure to an influenza virus, the immune system is prepared with circulating antibodies that identify and destroy the virus. … A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses.
Categories: Live Attenuated Influenza B Virus VaccineSynonyms: Influenza B virus B/Austria/1359417/2021 live, Influenza B virus B/Austria/1359417/2021 live (attenuated) antigenInfluenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB16903ApprovedWithdrawnUpon re-exposure to an influenza virus, the immune system is prepared with circulating antibodies that identify and destroy the virus. … A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses.
Categories: Inactivated Influenza A Virus VaccineSynonyms: Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (formaldehyde inactivated)Influenza B virus B/Singapore/WUH4618/2021 antigen (MDCK cell derived, propiolactone inactivated)
go.drugbank.com/drugs/DB16910ApprovedUpon re-exposure to an influenza virus, the immune system is prepared with circulating antibodies that identify and destroy the virus. … A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses.
Categories: Inactivated Influenza B Virus VaccineSynonyms: Influenza B virus B/Singapore/WUH4618/2021 antigen (MDCK cell derived, propiolactone inactivated)Influenza A virus A/Darwin/11/2021 (H3N2) antigen (MDCK cell derived, propiolactone inactivated)
go.drugbank.com/drugs/DB16914ApprovedWithdrawnUpon re-exposure to an influenza virus, the immune system is prepared with circulating antibodies that identify and destroy the virus. … A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses.
Categories: Inactivated Influenza A Virus VaccineSynonyms: Influenza A virus A/Darwin/11/2021 (H3N2) antigen (MDCK cell derived, propiolactone inactivated)