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Iophendylate
go.drugbank.com/drugs/DB01187ApprovedIophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). … In 1942 Van Wagenen (a neurosurgical colleague of Warrens, at the University of Rochester) identified Iophendylate as causing chemical meningitis in 30 patients where "space-displacing masses within the
Categories: Compounds used in a research, industrial, or household settingSynonyms: Ethyl 10-(p-iodophenyl)-undecanoate, Ethyl 10-(p-iodophenyl)undecylateTalquetamab
go.drugbank.com/drugs/DB16678ApprovedInvestigationalTalquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. … [L47765] Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and CD3 on T cells.
Synonyms: SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY; BISPECIFIC GAMMA4 HEAVY CHAIN HUMANIZED ANNADH
go.drugbank.com/drugs/DB00157ApprovedNutraceuticalIt forms NADP with the addition of a phosphate group to the 2' position of the adenosyl nucleotide through an ester linkage. (Dorland, 27th ed) … It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH).
Mixtures: Folika-V, HEPASELAMİN AMİNOASİT IV İNFÜZYON ÇÖZELTİSİ 500 ML SETLİ ŞİŞEN-alkyl ethylbenzyl dimethyl ammonium (C12-C14)
go.drugbank.com/drugs/DB11202ApprovedIt is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties. … N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties.
Drotaverine
go.drugbank.com/drugs/DB06751ApprovedWithdrawnDrotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4). … It is approved for use in Thailand as oral tablets or intramuscular injections.[L22689]
Eprosartan
go.drugbank.com/drugs/DB00876ApprovedInvestigationalEprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system.
Synonyms: (E)-2-butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acidAminophenazone
go.drugbank.com/drugs/DB01424ApprovedWithdrawnAminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. … In biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesBenzydamine
go.drugbank.com/drugs/DB09084ApprovedInvestigationalBenzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties … aspirin-like NSAIDs but facilitate benzydamine's mechanism of action as an effective locally-acting NSAID with local anaesthetic and analgesic properties.
Products: TANTUM VERDE P, VANTAL-VGremubamab
go.drugbank.com/drugs/DB15014InvestigationalGremubamab is under investigation in clinical trial NCT02255760 (Phase 1 Randomized Double-blind Placebo Controlled Study to Evaluate Safety and PK of MEDI3902 in Healthy Adults).
Ponezumab
go.drugbank.com/drugs/DB15135InvestigationalPonezumab is under investigation in clinical trial NCT00607308 (A Phase I, Single Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease).
Synonyms: PF-04360365