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Hypoxia-inducible factor 1
go.drugbank.com/bio_entities/BE0010297TargetHumansTranscription factor that functions as an obligate heterodimerization partner for several basic helix-loop-helix PER-ARNT-SIM (bHLH-PAS) proteins.
Synonyms: Member of PAS protein 1, PAS domain-containing protein 8Somatrem
go.drugbank.com/drugs/DB09098ApprovedWithdrawnnatural disposition of short stature should be considered a medical condition justifying medical treatment with such hormone therapy - especially when these hormone agents have been proven effective at
Mixtures: Protropin Inj Pws 10mg/vial, Protropin - Kit Im Sc 10mg/vialElvitegravir
go.drugbank.com/drugs/DB09101ApprovedInvestigationalElvitegravir was first licensed from Japan Tobacco in 2008 and developed by Gilead Sciences. It was FDA approved on August 27, 2012. … Although available as a single dose tablet, elvitegravir must be used in combination with an HIV protease inhibitor coadministered with ritonavir and another antiretroviral drug.
Mixtures: GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 90 ADET, GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 30 ADETAvilamycin
go.drugbank.com/drugs/DB11375ExperimentalVet approvedProducts: Surmax 100 Granule 100g per kgChemotaxis protein CheY
go.drugbank.com/bio_entities/BE0002023TargetEscherichia coli (strain K12)In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar … Overexpression of CheY in association with MotA and MotB improves motility of a ycgR disruption, suggesting there is an interaction (direct or indirect) between the c-di-GMP-binding flagellar brake protein
Polypeptides: Chemotaxis protein CheYCobicistat
go.drugbank.com/drugs/DB09065ApprovedInvestigationalAlthough it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered
Mixtures: GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 90 ADET, GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 30 ADETErdosteine
go.drugbank.com/drugs/DB05057ApprovedInvestigationalThis drug contains sulfhydryl groups which are released after erdosteine undergoes hepatic first pass metabolism. … 300mg twice daily reduced cough (both frequency and severity) and sputum viscosity more quickly and more effectively than placebo and reduced the adhesivity of sputum more effectively than ambroxol 30mg
Chemotaxis protein CheA
go.drugbank.com/bio_entities/BE0001431TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).
Polypeptides: Chemotaxis protein CheAEmtricitabine
go.drugbank.com/drugs/DB00879ApprovedInvestigational[L9019] Emtricitabine was granted FDA approval on 2 July 2003.[L9019]
Mixtures: GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 90 ADET, DESCOVY® 200MG/10MG TABLETAS RECUBIERTASImidapril
go.drugbank.com/drugs/DB11783InvestigationalImidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.
Products: PRILIUM 150MG POWDER FOR ORAL SOLUTION