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Displaying results 1271 - 1280 of 10000 in total
  1. Drug

    Norethisterone

    go.drugbank.com/drugs/DB00717
    ApprovedInvestigational

    [L9527,L10301,L10304,L10307] First derived in 1951 in Mexico City, norethisterone was originally intended for use as a remedy for irregular menstruation and endometriosis, and was not marketed for use … [A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol

    Synonyms: 19-nor-ethindrone, 19-nor-17α-ethynyltestosteroneInternational brands: Primolut-N
  2. Drug

    Trastuzumab deruxtecan

    go.drugbank.com/drugs/DB14962
    ApprovedInvestigational

    [A188988] Trastuzumab deruxtecan was developed by Daiichi Sankyo in collaboration with AstraZeneca and was first approved by the FDA in 2019.[L10842] … [L10842] It is classified as an antibody-drug conjugate. The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from other members of its class.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: ENHERTU POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIAL
  3. Drug

    Ergoloid mesylate

    go.drugbank.com/drugs/DB01049
    Approved

    [A32914] The mixture of ergoloid mesylate was first developed by Novartis and FDA approved on November 5, 1953, but this specific formulation is now discontinued. … [L2639]Later in 1991, the mixture of ergoloid mesylates was retaken by Sun Pharmaceutical Industries and approved by the FDA.

    Categories: Ergot Alkaloids and Derivatives, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: co-dergocrine mesilate, co-dergocrine mesylate
  4. Drug

    Activated charcoal

    go.drugbank.com/drugs/DB09278
    ApprovedInvestigational

    It is used as a gastric decontaminant and emergency medication to treat poisonings following excessive oral ingestion of certain medications or poisons by absorbing most drugs and toxins. … It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high affinity for various substances

    Mixtures: NO-GAS GIULIANI CARBOSYLANE, NO-GAS GIULIANI CARBOSYLANECategories: Antacids and Adsorbents, Alimentary Tract and Metabolism
  5. Drug

    (3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE

    go.drugbank.com/drugs/DB08186
    Experimental

    Synonyms: (3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE
  6. Drug

    Clofazimine

    go.drugbank.com/drugs/DB00845
    ApprovedInvestigationalWithdrawn

    treatments such as [rifampicin] and [isoniazid]. … [A203144] Although it carries _in vitro_ activity against other mycobacterium, such as _Mycobacterium tuberculosis_, it is generally considered an ineffective treatment in comparison to classic tuberculosis

    Categories: dapsone, rifampicin and clofazimineProducts: FAZIM 100MG CAPSULE
  7. Indication

    Astrocytoma

    go.drugbank.com/conditions/DBCOND0017186
    Drugs: Carmustine
    Synonyms: Astrocytoma, no ICD-O subtype, Astrocytoma, no ICD-O subtype (morphologic abnormality)
  8. Drug

    Eptinezumab

    go.drugbank.com/drugs/DB14040
    ApprovedInvestigational

    Eptinezumab is a fully-humanized IgG1 antibody manufactured using yeast (_Pichia pastoris_) and developed by Lundbeck Seattle Biopharmaceuticals. … [L12318] Eptinezumab has been specifically designed to bind to both alpha and beta forms of the human calcitonin gene-related peptide (CGRP).

    Categories: Amino Acids, Peptides, and ProteinsProducts: VYEPTI CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/ML
  9. Drug

    Nafarelin

    go.drugbank.com/drugs/DB00666
    ApprovedInvestigational

    Nafarelin has been used in the treatments of central precocious puberty and endometriosis.

    Categories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and InsulinsProducts: Synarel Nas Sol 2mg/ml
  10. Drug

    Tizanidine

    go.drugbank.com/drugs/DB00697
    ApprovedInvestigational

    It may also be caused by musculoskeletal injury [A177583]. Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition. … Initially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing spasticity by the presynaptic inhibition of excitatory neurotransmitters that cause firing of neurons

    Mixtures: MYOS -NOR F TABLETASProducts: SIRDALUD 2MG, TIZANIDIN TEVA 2MG TABL