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Vindesine
go.drugbank.com/drugs/DB00309ApprovedInvestigationalWithdrawnMajor side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).
Categories: Antineoplastic and Immunomodulating AgentsProducts: Eldisine Inj 5mg/2mlRavulizumab
go.drugbank.com/drugs/DB11580ApprovedInvestigational[A244460] It works by blocking terminal complement-mediated inflammation, cell activation, and cell lysis in blood disorders associated with the destruction of red blood cells, thrombosis, and impaired … [A244465] Ravulizumab was first approved by the FDA on December 21, 2018, for the treatment of paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome in children and adults.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: ULTOMIRIS ® RAVULIZUMAB 100MG/ML., Ultomiris 100mg/mL Concentrate For Solution For InfusionMagnesium chloride
go.drugbank.com/drugs/DB09407ApprovedInvestigationalMagnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Mixtures: Aminosyn II and Dextrose, Plasma-Lyte 148 and dextroseCategories: Alimentary Tract and Metabolism, Blood and Blood Forming OrgansPapaverine
go.drugbank.com/drugs/DB01113ApprovedInvestigationalAn alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. … The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
Categories: Drugs Used in Erectile Dysfunction, Alimentary Tract and MetabolismProducts: PAPAVERİN HCL GALEN 40 MG/2 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL, PAPAVERİN HCL GALEN 50 MG/2 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ, 10 AMPULAgalsidase beta
go.drugbank.com/drugs/DB00103ApprovedInvestigational[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009. … While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.
Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismProducts: FABRAZYME 5MG, FABRAZYME 5MG INJECTIONIdecabtagene vicleucel
go.drugbank.com/drugs/DB16665ApprovedInvestigational[L32858] Idecabtagene vicleucel was approved by the FDA on March 26, 2021 [L32863] and by the EMA on August 18, 2021.[L51003] … [A232563] Multiple myeloma is typically treated with an immunomodulatory agent like [lenalidomide],[A232593] a proteasome inhibitor like [bortezomib], or an anti-CD38 monoclonal antibody like [isatuximab
Synonyms: Anti-BCMA CAR T cellCategories: Amino Acids, Peptides, and Proteins, Antineoplastic cell and gene therapyGallium citrate Ga-67
go.drugbank.com/drugs/DB06784ApprovedAlthough the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation … Ga-67 scintigraphy (GS) cannot differentiate between tumor and acute inflammation. [NCI Thesaurus]
Categories: Inflammation and Infection DetectionProducts: GALLIUM CITRATE (GA67) INJ 37 MBQ/ML (82 MBQ), GALLIUM CITRATE (GA67) INJ 37 MBQ/ML (123 MBQ)Ergocalciferol
go.drugbank.com/drugs/DB00153ApprovedInvestigationalNutraceuticalErgocalciferol is an inactivated vitamin D analog.[A177526] It is synthesized by some plants in the presence of UVB light. … [A177637] The first approved product containing ergocalciferol under the FDA records was developed by US Pharm Holdings and was FDA approved in 1941.[L6058]
Mixtures: Cal/mag 2:1 With D, Calcium Mg and Zn Capsules With Vitamin DCategories: Diet, Food, and Nutrition, Vitamin D and AnaloguesSilver
go.drugbank.com/drugs/DB12965ApprovedInvestigationalSilver and its compounds have been used in trials studying the management of dental caries since the 1800s, and they may be found in dental pastes as an active ingredients. … Silver (Ag) is a chemical element that belongs in the family of transition metals in the periodic table. It has a high electrical conductivity, thermal conductivity, and reflectivity.
Mixtures: Silver Ion Rinse-free Hand Sanitizing Gel, iBrea Micro Silver Hand with Pure SilverCategories: Antiseptics and DisinfectantsRiociguat
go.drugbank.com/drugs/DB08931ApprovedInvestigationalRiociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for … Riociguat is marketed under the brand Adempas® by Bayer HealthCare Pharmaceuticals. Treatment with riociguat costs USD $7,500 for 30 days of treatment.
Synonyms: Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminateProducts: ADEMPAS FILM-COATED TABLET 1.0mg, Adempas 2.5mg film-coated tablet