Magnesium chloride

Identification

Name
Magnesium chloride
Accession Number
DB09407
Description

Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.

Type
Small Molecule
Groups
Approved
Structure
Thumb
Weight
Average: 95.211
Monoisotopic: 93.922747312
Chemical Formula
Cl2Mg
Synonyms
  • Anhydrous magnesium chloride
  • Magnesium chloride anhydrous

Pharmacology

Indication

Magnesium chloride is used in several medical and topical (skin related) applications. Magnesium chloride usp, anhydrous uses as electrolyte replenisher, pharmaceutic necessity for hemodialysis and peritoneal dialysis fluids.

Associated Conditions
Associated Therapies
Contraindications & Blackbox Warnings
Learn about our commercial Contraindications & Blackbox Warnings data.
Learn More
Pharmacodynamics

Magnesium is important as a cofactor in many enzymatic reactions in the body involving protein synthesis and carbohydrate metabolism (at least 300 enzymatic reactions require magnesium). Actions on lipoprotein lipase have been found to be important in reducing serum cholesterol and on sodium/potassium ATPase in promoting polarization (eg, neuromuscular functioning).

Mechanism of action

Mechanism of action of magnesium chloride studied in 10 adult volunteers. Results suggested magnesium ion in duodenum is relatively weak stimulus to pancreas and gall bladder. It is weak stimulant to cholecystokinin release and inhibits net jejunal water absorption. The oral administration of a single 800 mg dose of magnesium chloride in healthy volunteers resulted in a diminished rate of intraluminal lipid and protein digestion. The most pronounced effect of magnesium chloride, however, was a decreased gastric emptying rate of both test meals. After correction for gastric emptying, no differences were noted in intraluminal lipid or protein digestion. Therefore, the lower lipid levels noted after magnesium supplementation are unlikely to be the result of altered lipid assimilation. Magnesium chloride slows gastric emptying but does not influence lipid digestion.

Absorption

Oral: Inversely proportional to amount ingested; 40% to 60% under controlled dietary conditions; 15% to 36% at higher doses

Volume of distribution

Bone (50% to 60%); extracellular fluid (1% to 2%)

Protein binding

30%, to albumin

Metabolism

Magnesium levels are efficiently regulated by the kidneys. Magnesium also undergoes efficient enterohepatic circulation

Route of elimination

Magnesium is excreted in urine. Unabsorbed magnesium is excreted in feces

Half-life

Elimination half-life has been reported to be 27.7 hours following an overdose of 400 mEq magnesium in an adult.

Clearance

Maximum magnesium clearance is directly proportional to creatinine clearance.

Adverse Effects
Learn about our commercial Adverse Effects data.
Learn More
Toxicity

Mouse LD50 775mg/kg (intraperitoneal) Mouse LD50 : 7600mg/kg (oral) Rat LD 50 : 8100mg/kg (oral) Rat LD50 176mg/kg (intravenous) Severe toxicity occurs most often after intravenous infusions. It can also occur after chronic excessive oral doses, often in patients with renal insufficiency. Early manifestations are lethargy, hyporeflexia, followed by weakness, paralysis, hypotension, ECG changes (prolonged PR and QRS intervals), CNS depression, seizures, and respiratory depression. In overdose, magnesium impairs neuromuscular transmission, manifested as weakness and hyporeflexia.

Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbacavirAbacavir may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
AcarboseAcarbose may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
AceclofenacAceclofenac may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
AcemetacinAcemetacin may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
AcetaminophenAcetaminophen may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
AcetazolamideAcetazolamide may increase the excretion rate of Magnesium chloride which could result in a lower serum level and potentially a reduction in efficacy.
Acetylsalicylic acidAcetylsalicylic acid may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
AclidiniumAclidinium may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
AcrivastineMagnesium chloride may decrease the excretion rate of Acrivastine which could result in a higher serum level.
AcyclovirAcyclovir may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

    Learn more
  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

    Learn more
  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

    Learn more
  • Action
    Action

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

    Learn more
Food Interactions
  • Take with or without food. Taking magnesium supplements with food may reduce the risk of diarrhea.

Products

Product Ingredients
IngredientUNIICASInChI Key
Magnesium chloride hexahydrate02F3473H9O7791-18-6DHRRIBDTHFBPNG-UHFFFAOYSA-L
Magnesium chloride hydrateNot Available22756-14-5MJMDTFNVECGTEM-UHFFFAOYSA-L
Active Moieties
NameKindUNIICASInChI Key
Magnesium cationionicT6V3LHY83822537-22-0JLVVSXFLKOJNIY-UHFFFAOYSA-N
Chloride ionionicQ32ZN4869816887-00-6VEXZGXHMUGYJMC-UHFFFAOYSA-M
Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Cepasium Sup 100mgSuppositoryRectalLaboratoires Cortunon Inc.1980-12-311998-09-29Canada flag
ChloromagInjection, solution200 mg/1mLIntravenousMerit Pharmaceutical2011-06-11Not applicableUS flag
Magnesium ChlorideInjection, solution200 mg/1mLIntravenousAmerican Regent1990-09-302014-08-01US flag
Magnesium ChlorideInjection, solution200 mg/1mLIntravenousAmerican Therapeutic Medicines Inc.2009-05-012010-12-30US flag
Magnesium ChlorideInjection, solution200 mg/1mLIntravenousThe Torrance Company1990-09-032016-11-18US flag
Magnesium ChlorideInjection, solution200 mg/1mLIntravenousClaris Lifesciences Limited2009-10-072010-11-04US flag
Magnesium ChlorideInjection200 mg/1mLIntravenousMylan Institutional LLC2013-03-14Not applicableUS flag
Magnesium ChlorideInjection200 mg/1mLIntravenousMylan Teoranta2013-03-142015-01-15US flag
Magnesium-35 0.25 - 4.5Powder, for solutionHemodialysisAlthin Biopharm Inc.1988-12-311999-09-23Canada flag
Magnesium-35 0.5 - 4.5Powder, for solutionHemodialysisBaxter Laboratories1990-12-312002-08-01Canada flag
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

    Learn more
  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

    Learn more
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Formule 454LiquidOralLe Naturiste J.M.B. Inc.1980-12-312002-01-10Canada flag
Magnesium Chloride 606.5mgTabletOralBio Vita1987-12-312006-07-27Canada flag
Magnesium Liq 2.87mg/mlLiquidOralVitalab1990-12-312005-07-12Canada flag
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

    Learn more
  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

    Learn more
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
2.5% Travasol Amino Acid Injection With Electrolytes In 10% DextroseMagnesium chloride (25.5 mg) + Alanine (520 mg) + Arginine (290 mg) + Dextrose, unspecified form (10 g) + Dipotassium phosphate (130.5 mg) + Glycine (260 mg) + Histidine (120 mg) + Isoleucine (150 mg) + L-Lysine (145 mg) + Leucine (182.5 mg) + Methionine (100 mg) + Phenylalanine (140 mg) + Proline (170 mg) + Serine (125 mg) + Sodium acetate (170 mg) + Sodium chloride (29.3 mg) + Threonine (105 mg) + Tryptophan (45 mg) + Tyrosine (10 mg) + Valine (145 mg)SolutionIntravenousBaxter Corporation Clintec Nutrition Division1996-12-312015-08-05Canada flag
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose ClinimixMagnesium chloride (25.5 mg) + Alanine (520 mg) + Arginine (260 mg) + Dextrose, unspecified form (10 g) + Dipotassium phosphate (130.5 mg) + Glycine (520 mg) + Histidine (110 mg) + Isoleucine (120 mg) + L-Lysine hydrochloride (145 mg) + L-Leucine hydrochloride (155 mg) + Methionine (145 mg) + Phenylalanine hydrochloride (155 mg) + Proline (105 mg) + Sodium acetate (170 mg) + Sodium chloride (29.3 mg) + Threonine (105 mg) + Tryptophan (45 mg) + Tyrosine (10 mg) + Valine (115 mg)SolutionIntravenousBaxter Corporation Clintec Nutrition Division1993-12-312015-08-05Canada flag
2.5%travasol Amino Acid InJ.W.eleC.W.25%dexMagnesium chloride (25.5 mg) + Alanine (520 mg) + Arginine (290 mg) + Dextrose, unspecified form (25 g) + Dipotassium phosphate (130.5 mg) + Glycine (260 mg) + Histidine (120 mg) + Isoleucine (150 mg) + L-Lysine (145 mg) + Leucine (182.5 mg) + Methionine (100 mg) + Phenylalanine (140 mg) + Proline (170 mg) + Serine (125 mg) + Sodium acetate (170 mg) + Sodium chloride (29.3 mg) + Threonine (105 mg) + Tryptophan (45 mg) + Tyrosine (10 mg) + Valine (145 mg)LiquidIntravenousClintec Nutrition Company1996-07-301998-08-13Canada flag
2.75% Travas. Amino Acid InJ.W.elecw.25%dexMagnesium chloride (51 mg) + Alanine (570 mg) + Arginine (316 mg) + Dextrose, unspecified form (25 g) + Dipotassium phosphate (261 mg) + Glycine (283 mg) + Histidine (132 mg) + Isoleucine (165 mg) + L-Lysine (159.5 mg) + Leucine (201 mg) + Methionine (110 mg) + Phenylalanine (154 mg) + Proline (187 mg) + Serine (137.5 mg) + Sodium acetate (215.5 mg) + Sodium chloride (112 mg) + Threonine (115.5 mg) + Tryptophan (49.5 mg) + Tyrosine (11 mg) + Valine (159.5 mg)LiquidIntravenousClintec Nutrition Company1996-07-301998-08-13Canada flag
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose QuickmixMagnesium chloride (51 mg) + Alanine (570 mg) + Arginine (285 mg) + Dextrose, unspecified form (25 g) + Dipotassium phosphate (261 mg) + Glycine (570 mg) + Histidine (120.5 mg) + Isoleucine (131.5 mg) + L-Lysine hydrochloride (159 mg) + L-Leucine hydrochloride (170 mg) + Methionine (159 mg) + Phenylalanine hydrochloride (170 mg) + Proline (115 mg) + Sodium acetate (215.5 mg) + Sodium chloride (112 mg) + Threonine (115 mg) + Tryptophan (49.5 mg) + Tyrosine (11 mg) + Valine (126 mg)SolutionIntravenousBaxter Corporation Clintec Nutrition Division1996-02-022007-08-02Canada flag
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose QuickmixMagnesium chloride (51 mg) + Alanine (570 mg) + Arginine (285 mg) + Dextrose, unspecified form (5 g) + Dipotassium phosphate (215.5 mg) + Glycine (570 mg) + Histidine (120.5 mg) + Isoleucine (131.5 mg) + L-Lysine hydrochloride (159 mg) + L-Leucine hydrochloride (170 mg) + Methionine (159 mg) + Phenylalanine hydrochloride (170 mg) + Proline (115 mg) + Sodium acetate (256 mg) + Sodium chloride (112 mg) + Threonine (115 mg) + Tryptophan (49.5 mg) + Tyrosine (11 mg) + Valine (126 mg)SolutionIntravenousBaxter Corporation Clintec Nutrition Division1993-12-312007-08-02Canada flag
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.Magnesium chloride (51 mg) + Alanine (570 mg) + Arginine (316 mg) + Dextrose, unspecified form (5 g) + Dipotassium phosphate (261 mg) + Glycine (283 mg) + Histidine (132 mg) + Isoleucine (165 mg) + L-Lysine (159.5 mg) + Leucine (201 mg) + Methionine (110 mg) + Phenylalanine (154 mg) + Proline (187 mg) + Serine (137.5 mg) + Sodium acetate (215 mg) + Sodium chloride (112 mg) + Threonine (115.5 mg) + Tryptophan (49.5 mg) + Tyrosine (11 mg) + Valine (159.5 mg)LiquidIntravenousClintec Nutrition Company1996-12-311999-08-10Canada flag
4.25% Travasol Amino Acid Injection With Electrolytes In 10% DextroseMagnesium chloride (51 mg) + Alanine (880 mg) + Arginine (489 mg) + Dextrose, unspecified form (10 g) + Dipotassium phosphate (261 mg) + Glycine (438 mg) + Histidine (204 mg) + Isoleucine (255 mg) + L-Lysine hydrochloride (246.5 mg) + Leucine (310 mg) + Methionine (170 mg) + Phenylalanine (238 mg) + Proline (289 mg) + Serine (212.5 mg) + Sodium acetate (297 mg) + Sodium chloride (77 mg) + Threonine (178.5 mg) + Tryptophan (76.5 mg) + Tyrosine (17 mg) + Valine (246.5 mg)SolutionIntravenousBaxter Corporation Clintec Nutrition Division1996-12-312015-08-05Canada flag
4.25% Travasol Amino Acid Injection With Electrolytes In 20% DextroseMagnesium chloride (51 mg) + Alanine (880 mg) + Arginine (489 mg) + Dextrose, unspecified form (20 g) + Dipotassium phosphate (261 mg) + Glycine (438 mg) + Histidine (204 mg) + Isoleucine (255 mg) + L-Lysine hydrochloride (246.5 mg) + Leucine (310 mg) + Methionine (170 mg) + Phenylalanine (238 mg) + Proline (289 mg) + Serine (212.5 mg) + Sodium acetate (297 mg) + Sodium chloride (77 mg) + Threonine (178.5 mg) + Tryptophan (76.5 mg) + Tyrosine (17 mg) + Valine (246.5 mg)SolutionIntravenousBaxter Corporation Clintec Nutrition Division1996-12-312007-08-02Canada flag
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose QuickmixMagnesium chloride (51 mg) + Alanine (880 mg) + Arginine (440 mg) + Dextrose, unspecified form (20 g) + Dipotassium phosphate (261 mg) + Glycine (880 mg) + Histidine (186 mg) + Isoleucine (203 mg) + L-Lysine hydrochloride (246 mg) + L-Leucine hydrochloride (263 mg) + Methionine (246 mg) + Phenylalanine hydrochloride (263 mg) + Proline (178 mg) + Sodium acetate (297 mg) + Sodium chloride (77 mg) + Threonine (178 mg) + Tryptophan (76 mg) + Tyrosine (17 mg) + Valine (195 mg)SolutionIntravenousBaxter Corporation Clintec Nutrition Division1995-12-312007-08-02Canada flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
ChloromagMagnesium chloride hexahydrate (200 mg/1mL)Injection, solutionIntravenousMerit Pharmaceutical2011-06-11Not applicableUS flag
ClinimixMagnesium chloride hexahydrate (1.02 g/2L) + Alanine (17.60 g/2L) + Arginine (9.78 g/2L) + Calcium chloride dihydrate (0.66 g/2L) + D-glucose monohydrate (300.00 g/2L) + Dipotassium phosphate (5.22 g/2L) + Glycine (8.76 g/2L) + Histidine (4.08 g/2L) + Isoleucine (5.10 g/2L) + L-Lysine (4.93 g/2L) + Leucine (6.20 g/2L) + Methionine (3.40 g/2L) + Phenylalanine (4.76 g/2L) + Proline (5.78 g/2L) + Serine (4.25 g/2L) + Sodium acetate trihydrate (5.94 g/2L) + Sodium chloride (1.54 g/2L) + Threonine (3.57 g/2L) + Tryptophan (1.53 g/2L) + Tyrosine (0.34 g/2L) + Valine (4.93 g/2L)SolutionIntravenousBaxter Healthcare Corporation2017-10-252019-11-30US flag
ClinimixMagnesium chloride hexahydrate (0.51 g/1L) + Alanine (5.70 g/1L) + Arginine (3.17 g/1L) + Calcium chloride dihydrate (0.33 g/1L) + D-glucose monohydrate (75.00 g/1L) + Dipotassium phosphate (2.61 g/1L) + Glycine (2.84 g/1L) + Histidine (1.32 g/1L) + Isoleucine (1.65 g/1L) + L-Lysine (2.00 g/1L) + Leucine (2.01 g/1L) + Methionine (1.10 g/1L) + Phenylalanine (1.54 g/1L) + Proline (1.87 g/1L) + Serine (1.38 g/1L) + Sodium acetate trihydrate (2.16 g/1L) + Sodium chloride (1.12 g/1L) + Threonine (1.16 g/1L) + Tryptophan (0.50 g/1L) + Tyrosine (0.11 g/1L) + Valine (1.60 g/1L)SolutionIntravenousBaxter Healthcare Corporation2017-10-252019-11-30US flag
ClinimixMagnesium chloride hexahydrate (0.51 g/1L) + Alanine (5.70 g/1L) + Arginine (3.17 g/1L) + Calcium chloride dihydrate (0.33 g/1L) + D-glucose monohydrate (100.00 g/1L) + Dipotassium phosphate (2.61 g/1L) + Glycine (2.84 g/1L) + Histidine (1.32 g/1L) + Isoleucine (1.65 g/1L) + L-Lysine (2.00 g/1L) + Leucine (2.01 g/1L) + Methionine (1.10 g/1L) + Phenylalanine (1.54 g/1L) + Proline (1.87 g/1L) + Serine (1.38 g/1L) + Sodium acetate trihydrate (2.16 g/1L) + Sodium chloride (1.12 g/1L) + Threonine (1.16 g/1L) + Tryptophan (0.50 g/1L) + Tyrosine (0.11 g/1L) + Valine (1.60 g/1L)SolutionIntravenousBaxter Healthcare Corporation2017-10-252019-11-30US flag
Cytosol Ophthalmics - Balanced Salt SolutionMagnesium chloride hexahydrate (30 mg/1mL) + Calcium chloride dihydrate (48 mg/1mL) + Potassium chloride (75 mg/1mL) + Sodium acetate trihydrate (3.90 mg/1mL) + Sodium chloride (6.40 mg/1mL) + Sodium citrate dihydrate (1.70 mg/1mL)SolutionIrrigationBiomet Biologics2010-01-012010-09-04US flag
Dianeal for Peritoneal DialysisMagnesium chloride hexahydrate (0.051 g/1000mL) + Calcium chloride dihydrate (0.184 g/1000mL) + D-glucose (38.6 g/1000mL) + Sodium lactate (4.48 g/1000mL) + Sodium chloride (5.38 g/1000mL)Injection, solutionIntraperitonealBaxter Healthcare Corporation2014-10-272016-12-31US flag
Dianeal for Peritoneal DialysisMagnesium chloride hexahydrate (0.051 g/1000mL) + Calcium chloride dihydrate (0.184 g/1000mL) + D-glucose (22.7 g/1000mL) + Sodium lactate (4.48 g/1000mL) + Sodium chloride (5.38 g/1000mL)Injection, solutionIntraperitonealBaxter Healthcare Corporation2014-10-272016-12-31US flag
Dianeal for Peritoneal DialysisMagnesium chloride hexahydrate (0.051 g/1000mL) + Calcium chloride dihydrate (0.184 g/1000mL) + D-glucose (13.6 g/1000mL) + Sodium lactate (4.48 g/1000mL) + Sodium chloride (5.38 g/1000mL)Injection, solutionIntraperitonealBaxter Healthcare Corporation2014-10-272016-12-31US flag
Hyperlyte CRMagnesium chloride hexahydrate (0.51 g/20mL) + Calcium chloride dihydrate (0.37 g/20mL) + Potassium acetate (1.96 g/20mL) + Sodium acetate trihydrate (0.68 g/20mL) + Sodium chloride (1.17 g/20mL)Injection, solution, concentrateIntravenousB. Braun Medical Inc.2012-04-12Not applicableUS flag
Kaydia PatchMagnesium chloride hexahydrate (2 g/100g) + Arnica montana flower (0.5 g/100g) + Curcumin (1 g/100g) + Ginger (0.5 g/100g) + Piperine (0.2 g/100g) + Pyridoxine (1 g/100g) + Thiamine chloride (1 g/100g)PatchTopicalStrong Current Enterprises Limited2020-05-01Not applicableUS flag

Categories

ATC Codes
A12CC01 — Magnesium chlorideB05XA11 — Magnesium chloride
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as alkaline earth metal chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is a lanthanide.
Kingdom
Inorganic compounds
Super Class
Mixed metal/non-metal compounds
Class
Alkaline earth metal salts
Sub Class
Alkaline earth metal chlorides
Direct Parent
Alkaline earth metal chlorides
Alternative Parents
Inorganic chloride salts
Substituents
Alkaline earth metal chloride / Inorganic chloride salt / Inorganic salt
Molecular Framework
Not Available
External Descriptors
inorganic chloride, magnesium salt, magnesium halide (CHEBI:6636)

Chemical Identifiers

UNII
59XN63C8VM
CAS number
7786-30-3
InChI Key
TWRXJAOTZQYOKJ-UHFFFAOYSA-L
InChI
InChI=1S/2ClH.Mg/h2*1H;/q;;+2/p-2
IUPAC Name
magnesium(2+) dichloride
SMILES
[Mg++].[Cl-].[Cl-]

References

General References
  1. DRUGS.COM [Link]
  2. Pubchem [Link]
  3. Toxnet [Link]
  4. ChemIDplus [Link]
KEGG Compound
C07755
PubChem Compound
5360315
PubChem Substance
347827844
ChemSpider
22987
RxNav
1311539
ChEBI
6636
ChEMBL
CHEMBL2219642
Wikipedia
Magnesium_chloride
AHFS Codes
  • 40:34.00* — Hemodialysis Solution
  • 88:29.00* — Minerals

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Active Not RecruitingTreatmentImpaired kidney function1
4CompletedTreatmentAPD / Continuous ambulatory peritoneal dialysis therapy / Diabetes / ESRD1
4CompletedTreatmentChronic Kidney Disease (CKD) / Peritoneal dialysis therapy1
4RecruitingTreatmentHypovolaemia1
4TerminatedTreatmentDehydration / Gastroenteritis1
4Unknown StatusBasic ScienceNephrotoxicity1
4WithdrawnTreatmentHypertriglyceridemias / Peritoneal dialysis therapy1
3Active Not RecruitingPreventionAcute Kidney Injury (AKI) / Illness, Critical1
3Active Not RecruitingTreatmentDelayed Graft Function / End Stage Kidney Disease / Kidney Transplant; Complications1
3CompletedTreatmentAnaesthesia therapy1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solution257 mg/1L
Injection, solutionIntravenous2.5 g/500mL
SolutionIntravenous2.453 g
Powder, for solutionIntraocular
SolutionIntraocular
SolutionIntraperitoneal951 mg/L
SolutionIntraperitoneal0.1838 g/L
SolutionIntraperitoneal0.2573 g/L
SolutionOphthalmic
SolutionIntraocular; Irrigation1950 mg
SolutionIntravenous0.64 g/100ml
SolutionIntravenous5 g/100ml
SolutionIntravenous50 g/L
SolutionIrrigation48 mg/100mL
Kit; solutionIntraocular
SolutionIntraperitoneal0.0003 g
Injection, solutionIntracardiac16 mmol/20mL
SolutionIntra-arterial
Solution6340 mg/L
SuppositoryRectal
SolutionIrrigation
Injection, solution3.25 g/1mL
SolutionIntraperitoneal
SolutionIntravenous6.4 g/L
Injection, solutionIntraperitoneal220 mg
SolutionIntraperitoneal; Irrigation18.3 mg
SolutionIntraperitoneal18.3 mg
Injection, solutionIntraperitoneal
LiquidHemodialysis
SolutionHemodialysis
Injection, solutionIntraperitoneal18.3 mg/100mL
Solution22.7 g/L
Solution13.6 g/L
SolutionIntraperitoneal22.7 g/L
Solution38.6 g/L
SolutionIntraperitoneal13.6 g/L
SolutionIntraperitoneal38.6 g/L
SolutionIntravenous4.21 g/1000ml
SolutionIntrathecal
SolutionIntraperitoneal0.0257 g
Solution75 g/L
Injection, solutionIntraperitoneal25.7 mg/100mL
SolutionIntraperitoneal7.5 g/100mL
SolutionIntravenous1.63 g
SprayOral7.3 mg/50mL
Solution, concentrate9 g/1L
Solution, concentrate6.43 g/1L
SolutionOral30 mg
SolutionOral0.275 g
SolutionOral275 mg
SolutionIntraperitoneal7.5 %
LiquidIntraperitoneal
SolutionHemodialysis; Intraperitoneal
LiquidIntraocular
Solution0.64 g/100ml
SolutionIntravenous0.64 %
SolutionIntravenous0.03 %
SolutionIntravenous5 %
SolutionIntravenous0.37 %
SolutionIntravenous
PatchTopical
InjectionIntravenous200 mg/1mL
Injection, solutionIntravenous200 mg/1mL
SolutionOral5 g/100mL
Tablet, coatedOral
SolutionOral10 g/100mL
TabletOral
Tablet, delayed releaseOral598 mg/1
LiquidOral
PowderHemodialysis
Powder, for solutionHemodialysis
TabletOral
Syrup5 g/100mL
LiquidBuccal
SprayBuccal
SolutionIntravenous0.368 g
LiquidIntravenous
Kit; solutionIntraocular; Irrigation
SolutionIntravenous5.5 g/100ml
Solution0.53 g/100ml
Solution16 g/L
Injection, emulsionIntravenous1.6 g/100mL
Injection, emulsion; injection, solutionIntravenous3.2 g/100mL
Injection, solution, concentrateIntravenous
SolutionIntraperitoneal510 mg/l
Injection, emulsionIntravenous1.6 g
InjectionIntravenous2.27 g/l
InjectionIntravenous4.12 g/l
SolutionIntravenous7.14 g
SolutionIntravenous9.52 g
SolutionIntravenous11.9 g
EmulsionIntravenous6.41 g
EmulsionIntravenous9.61 g
EmulsionIntravenous12.82 g
EmulsionIntravenous4 g
SolutionIntraocular; Ophthalmic7.8 mg
Injection, solutionIntraperitoneal32 mg/100mL
SolutionOral29.4 mg
EmulsionIntravenous
EmulsionIntravenous3 g
SolutionIntraperitoneal15 g/L
SolutionIntraperitoneal25 g/L
SolutionIntravenous25 g/L
SolutionIntraperitoneal42.5 g/L
IrrigantIrrigation
SolutionIntravenous368 mg
Injection, solutionIntravenous
Injection, solutionIntra-arterial
Solution
SolutionIntravenous0.035 %
Injection, solutionIntravenous5 %
Injection, solutionIntravenous0.03 %
Solution3.2 g/100mL
Solution1.6 g/100mL
KitHemodialysis
SolutionHemodialysis; Intravenous
Injection, solution514.5 mg/100mL
SolutionBuccal; Oral; Topical16.2 mg
AerosolOral
SolutionIntraperitoneal25.7 mg
SolutionIntraocular; Irrigation0.39 g
Injection, solutionIntracardiac13.54 mg/20mL
InjectionIntravenous
SolutionIntravenous594 mg
SolutionIntravenous6 g/100mL
Injection, solutionIntravenous30 g/500mL
Prices
Not Available
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)Region
US5945449No1999-08-312017-10-31US flag
US7300674No2007-11-272023-03-04US flag
US6077836No2000-06-202017-06-20US flag
US6248726No2001-06-192018-06-19US flag
US7084130No2006-08-012021-11-29US flag
Additional Data Available
  • Filed On
    Filed On

    The date on which a patent was filed with the relevant government.

    Learn more

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility19.3 mg/mLALOGPS
logP1.16ALOGPS
logP-0.57ChemAxon
logS-0.69ALOGPS
pKa (Strongest Acidic)3.09ChemAxon
Physiological Charge2ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on November 30, 2015 12:10 / Updated on October 21, 2020 01:55

Logo pink
Are you a
new drug developer?
Contact us to learn more about our customized products and solutions.
Logo pink
Stay in the know!
As part of our commitment to providing the most up-to-date drug information, we will be releasing #DrugBankUpdates with our newly added curated drug pages.
#DrugBankUpdates