Magnesium chloride is an ionic compound and source of magnesium used for electrolyte replenishment and conditions associated with magnesium deficiencies. Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
- Mechanism
- Curator reviewed
Mechanism of action of magnesium chloride studied in 10 adult volunteers. Results suggested magnesium ion in duodenum is relatively weak stimulus to pancreas and gall bladder. It is weak stimulant to cholecystokinin release and inhibits net jejunal water absorption. The oral administration of a single 800 mg dose of magnesium chloride in healthy volunteers resulted in a diminished rate of intraluminal lipid and protein digestion. The most pronounced effect of magnesium chloride, however, was a decreased gastric emptying rate of both test meals. After correction for gastric emptying, no differences were noted in intraluminal lipid or protein digestion. Therefore, the lower lipid levels noted after magnesium supplementation are unlikely to be the result of altered lipid assimilation. Magnesium chloride slows gastric emptying but does not influence lipid digestion.
- Primary indication
- Magnesium chloride is used in several medical and topical (skin related) applications.Curator reviewed · 19 structured indications
- Formula / weight
- Cl2Mg · 95.211 g/mol (avg)
- First approval
- Canada, 1997 · United States, 1969
- Brand names
Resolves to
TWRXJAOTZQYOKJ-UHFFFAOYSA-LSMILES[Mg++].[Cl-].[Cl-]What you can answer from here — as of September 30, 2026
Which drugs share a target with Magnesium chloride, and which of those have an active Phase 3 trial?
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